Results 41 to 50 of about 15,641,518 (273)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Doctoral Education for Technology-Enhanced Learning in Europe: report [PDF]
, 2022 This report informs about the state of doctoral education in the area of Technology-Enhanced Learning (TEL) in Europe. The report aims to inform policy decisions in doctoral education and in the implementation of these policies.
Albó, Laia +16 more
core
Benchmarks for technology enhanced learning
, 2014 The ACODE benchmarks have been developed to assist institutions in their practice of delivering a quality technology enhanced learning experience for their students and staff (recognising that some institutions refer to their practice with terms such as ...
Obexer, Regina +5 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Technology-Enhanced and Collaborative Learning
, 2018 Technology-enhanced, collaborative and blended learning settings can promote more effective approaches to teaching, learning and assessment when context, agency and individual characteristics are taken into account.
Martin, Stewart, Notari, Michele
core +1 more source
Digital Teaching and Digital Medicine: A national initiative is needed
GMS Journal for Medical Education, 2018 The advancing digitization of the healthcare system requires that in the future digital skills should be communicated to students much more. In addition, digital teaching and learning technologies should be used wherever they offer real benefits over ...
Haag, Martin +4 more
doaj +1 more source
Research in Learning Technology, 2021 Collaborative learning offers benefits but there is insufficient information on how students perceive specific digital tools supporting collaborative learning and whether there are content-related differences in students’ perceptions.
Kosha J. Mehta +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source