Results 51 to 60 of about 1,225,537 (291)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Technology-enhanced Personalised Learning: Untangling the Evidence [PDF]

, 2018
Technology-enhanced personalised learning is not yet common in Germany, which is why we have tasked scientists with summarising the current status of international research on the matter.
Anastopoulou, Stamatina, Holmes, Wayne, Mavrikis, Manolis, Schaumburg, Heike   +3 more
core  

An activity theory approach to analysing student learning of human anatomy using a 3D-printed model and a digital resource

BMC Medical Education
Introduction The availability of different tools for teaching and learning has made it challenging for educators to determine which tools are more effective and appropriate for helping students achieve learning outcomes.
Jason Wen Yau Lee, Li Xiang Tessa Low, Dennis Wenhui Ong, Fernando Bello, Reuben Chee Cheong Soh   +4 more
doaj   +1 more source

Methods and models of next generation technology enhanced learning - White Paper [PDF]

, 2011
Our understanding of learning with technology is increasingly lagging behind technological advancements, such that it is no longer possible to fully understand learning with technologies without bringing together evidence from practice-based experiences ...
Clough, Gill, Ferguson, Rebecca, Kukulska-Hulme, Agnes, Mwanza-Simwami, Daisy, Sharples, Mike, Whitelock, Denise   +5 more
core  

Research ethics and participatory research in an interdisciplinary technology-enhanced learning project [PDF]

, 2013
This account identifies some of the tensions that became apparent in a large interdisciplinary technology-enhanced learning project as its members attempted to maintain their commitment to responsive, participatory research and development in ...
Carmichael, Patrick, Tracy, Frances
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Development of personalized profiles of students with autism spectrum disorder for interactive interventions with robots to enhance language and social skills

Frontiers in Psychiatry
The inclusion of students with autism spectrum disorder (ASD) in mainstream education (primary and secondary, in the range of 4-5 to 8-10 years old) is a complex task that has long challenged both educators and health professionals.
Javier Herrero-Martín, David Fonseca, Selene Caro-Via, Xavi Canaleta   +3 more
doaj   +1 more source

Improving the Quality of Technology-Enhanced Learning for Computer Programming Courses [PDF]

, 2014
Teaching computing courses is a major challenge for the majority of lecturers in Libyan higher learning institutions. These courses contain numerous abstract concepts that cannot be easily explained using traditional educational methods.
Impes, Ahmed, Othman, Aisha, Pislaru, Crinela   +2 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Technology-enhanced Learning

, 2017
A report commissioned by the National Forum for the Enhancement of Teaching and Learning in Higher Education on summary results arising from the National Forum 20Qs TEL SURVEY (March 2015).
  +4 more sources