Results 41 to 50 of about 5,517,695 (292)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Manufactura biológica e inteligente: atributos de la vida aplicados al desarrollo tecnológico

open access: yesIngeniería e Investigación, 2009
Los entornos altamente dinámicos caracterizados por el predominio del conocimiento como motor del desarrollo hacen que sea necesario abordar problemáticas específicas a través de enfoques multidisciplinarios.
Claudia Nelcy Jiménez Hernández   +2 more
doaj  

Selected Instruments for Management of Technology Development [PDF]

open access: yes, 2013
Polska dysponuje pewnymi możliwościami rozwijania nowoczesnych technologii, także tych, które aktualnie znajdują się w pierwszych fazach cyklu życia (np. nanotechnologii, spintroniki, fizykochemii zjawisk powierzchniowych, robotyki itd.), i mają wysoki
Piasecki, Bogdan, Rogut, Anna
core  

Drones: Innovative Technology for Use in Precision Pest Management. [PDF]

open access: yes, 2020
Arthropod pest outbreaks are unpredictable and not uniformly distributed within fields. Early outbreak detection and treatment application are inherent to effective pest management, allowing management decisions to be implemented before pests are well ...
de Lange, Elvira S   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Strategies to Mitigate Technoference Among Indian Youth: A Qualitative Study Using Semi-Structured Interviews

open access: yesJournal of Psychiatry Spectrum
Background: The growing use of digital devices has led to the phenomenon of “technoference” – technology-induced disruptions in interpersonal communication, particularly among youth.
M. S. Neeraj   +3 more
doaj   +1 more source

Online Technology Management Student Tutorial Case Study [PDF]

open access: yes, 2010
This paper presents a case study of implementing online video-based tutorials to enhance student learning. Initially, these tutorials were developed using a software product, Camtasia, to mitigate learning differences between traditional-based classrooms
Kuzma, Joanne
core   +1 more source

Development of Nano-economy as a Factor of Forming the Effective National Innovation System of Singapore [PDF]

open access: yes, 2016
The article reveals the theoretical and methodological interpretation of the innovation system, when it determined the structure of the national innovation system. It is noted that the components of the national innovation system are elements, stages and
Ostapenko, T. (Tetiana)
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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