Results 1 to 10 of about 39,048 (231)

Cell-free protein synthesis: advances on production process for biopharmaceuticals and immunobiological products

BioTechniques, 2021
Biopharmaceutical products are of great importance in the treatment or prevention of many diseases and represent a growing share of the global pharmaceutical market.
Camila Hiromi Chiba, Marcos Camargo Knirsch, Adriano Rodrigues Azzoni, Antonio R Moreira, Marco Antonio Stephano   +4 more
doaj   +1 more source

Endothelium-Derived Nitric Oxide Contributes to the Vasorelaxant Response Induced by Mesoionic 2-(4-Chlorophenyl)-3-methyl-4-(4-methoxyphenyl)-1;3-thiazolium-5-thyolate (CMMTT) in Rats

Journal of Pharmacological Sciences, 2009
.: This study was performed to investigate the mechanisms involved in the vasorelaxation induced by mesoionic 2-(4-chlorophenyl)-3-methyl-4-(4-methoxyphenyl)-1;3-thiazolium-5-thyolate (CMMTT), a newly synthesized mesoionic compound, in rat superior ...
Karla Veruska Marques Cavalcante, Nádja de Azevedo Correia, Katy Lísias Gondim Dias, Darizy Flávia Silva, José Couras Silva-Filho, Islania Giselia Albuquerque Araújo, Bruno Farias Lira, Petrônio Athayde-Filho, Isac Almeida Medeiros   +8 more
doaj   +1 more source

Endochitinase and Chitobiosidase Production by Marine Aeromonas caviae CHZ306: Establishment of Nitrogen Supplementation

Bioengineering, 2023
Aeromonas caviae CHZ306, a marine-derived bacterium isolated from zooplankton, can use chitin (a polymer of a β-(1,4)-linked N-acetyl-D-glucosamine) as a carbon source.
Flavio Cardozo, Valker Feitosa, Omar Pillaca-Pullo, Adalberto Pessoa   +3 more
doaj   +1 more source

Abdominal chicken fat fractionation

Grasas y Aceites, 2002
The objective of this study was to determine physical and chemical properties of the products from the abdominal chicken fat fractionation. Melting point, consistency, solid fat content, fatty acid composition, iodine and saponification values were ...
Chiu Chih Ming, Luiz Antonio Gioielli, Victor Sotero Solis   +2 more
doaj   +1 more source

Pulmonary Administration: Strengthening the Value of Therapeutic Proximity

Frontiers in Medicine, 2020
In recent years inhaled systems have shown momentum as patient-personalized therapies emerge. A significant improvement in terms of therapeutic efficacy and/or reduction adverse systemic effects is anticipated from their use owing these systems regional ...
Mafalda A. Videira, Jordi Llop, Carolina Sousa, Bruna Kreutzer, Unai Cossío, Ben Forbes, Isabel Vieira, Nuno Gil, Beatriz Silva-Lima   +8 more
doaj   +1 more source

α-Gluco-oligosaccharide in the research and development of a polymeric material for modified drug delivery

Heliyon, 2019
This research aimed to analyse the influence of the incorporation of α-gluco-oligosaccharide (GOS-α) in the formation of isolated films of different combinations of polymethyl by applying physicochemical analyses such as Fourier transform infrared (FTIR),
Frederico Minardi de Oliveira, Élcio José Bunhak, Leandro Freire dos Santos, Priscila Debastiani Barros, Osvaldo Albuquerque Cavalcanti   +4 more
doaj   +1 more source

Development of Guar Gum Hydrogel Containing Sesamol-Loaded Nanocapsules Designed for Irritant Contact Dermatitis Treatment Induced by Croton Oil Application

Pharmaceutics, 2023
Irritant contact dermatitis is usually treated with corticosteroids, which cause expressive adverse effects. Sesamol is a phenolic compound with anti-inflammatory and antioxidant properties.
Vinicius Costa Prado, Kauani Moenke, Bárbara Felin Osmari, Natháli Schopf Pegoraro, Sara Marchesan Oliveira, Letícia Cruz   +5 more
doaj   +1 more source

Synthesis, Stability Studies, and Antifungal Evaluation of Substituted α- and β-2,3-Dihydrofuranaphthoquinones against Sporothrix brasiliensis and Sporothrix schenckii

Molecules, 2019
Sporotrichosis is a neglected fungal infection caused by Sporothrix spp., which have a worldwide distribution. The standard antifungal itraconazole has been recommended as a first-line therapy.
Patricia Garcia Ferreira, Luana Pereira Borba-Santos, Leticia Lorena Noronha, Caroline Deckman Nicoletti, Marcella de Sá Haddad Queiroz, Fernando de Carvalho da Silva, Sônia Rozental, Débora Omena Futuro, Vitor Francisco Ferreira   +8 more
doaj   +1 more source

Effects of Oxygen Transference on Protease Production by Rhodotorula mucilaginosa CBMAI 1528 in a Stirred Tank Bioreactor

Bioengineering, 2022
Microbial proteases, especially aspartic proteases, are an essential group of enzymes produced from different microorganisms. Microbial proteases have several applications, mainly in the food, beverage, cosmetic, and pharmaceutical industries, due to ...
Suellen Machado, Valker Feitosa, Omar Pillaca-Pullo, Luciana Lario, Lara Sette, Adalberto Pessoa, Harley Alves   +6 more
doaj   +1 more source

Karaya/Gellan-Gum-Based Bilayer Films Containing 3,3′-Diindolylmethane-Loaded Nanocapsules: A Promising Alternative to Melanoma Topical Treatment

Pharmaceutics, 2023
This study aimed to incorporate nanocapsules containing 3,3′-diindolylmethane (DIM) with antitumor activity into a bilayer film of karaya and gellan gums for use in topical melanoma therapy.
Jéssica Brandão Reolon, Camila Parcianello Saccol, Bárbara Felin Osmari, Daiane Britto de Oliveira, Vinicius Costa Prado, Fernanda Licker Cabral, Lucas Saldanha da Rosa, Giancarlo Cervo Rechia, Daniela Bitencourt Rosa Leal, Letícia Cruz   +9 more
doaj   +1 more source