Results 21 to 30 of about 1,904 (138)

Molluscicidal and Cercaricidal Effects of Myrciaria floribunda Essential Oil Nanoemulsion

Molecules, 2023
Schistosomiasis is a tropical disease transmitted in an aqueous environment by cercariae from the Schistosoma genus. This disease affects 200 million people living in risk areas around the world. The control of schistosomiasis is realized by chemotherapy,
Francisco Paiva Machado, Diogo Folly, Ricardo Esteves, Bettina Monika Ruppelt, Victoria Marques da Silva, Ana Paula dos Santos Matos, José Augusto Albuquerque dos Santos, Leonardo da Silva Rangel, Marcelo Guerra Santos, Natalia Lidmar von Ranke, Carlos Rangel Rodrigues, Eduardo Ricci-Junior, Leandro Rocha, Robson Xavier Faria   +13 more
doaj   +1 more source

EXCIPIENTES PARA A PRODUÇÃO DE COMPRIMIDOS POR COMPRESSÃO DIRETA

Infarma: Pharmaceutical Sciences, 2013
O interesse da indústria farmacêutica na produção de comprimidos através da compressão direta tem aumentado nos últimos anos, principalmente por ser um método de produção de fácil controle e com menor tempo de processo, levando a uma maior produtividade ...
Tiago Rafael SAUSEN, Paulo MAYORGA
doaj   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Oportunidades na indústria de medicamentos e a lógica do desenvolvimento local baseado nos biomas brasileiros: bases para a discussão de uma política nacional [PDF]

Cadernos de Saúde Pública, 2007
Este trabalho traz para a Saúde Pública a discussão de novos conceitos sobre o desenvolvimento tecnológico de medicamentos de origem vegetal, constatando as oportunidades no mercado da indústria farmacêutica tanto para a produção de medicamentos ...
Glauco de Kruse Villas Bôas, Carlos Augusto Grabois Gadelha   +1 more
doaj  

Isolation and Characterization of the ‘Flavonoid Crystals’ of Three Species of : Chemotaxonomic Considerations of the Genera and

Natural Product Communications, 2007
The isolation of fragnettin, the so called ‘flavonoid crystals’, from three species of Prosthechea , namely P. fragrans, P. vespa and P. caetensis , and its characterization as 8- C -β-D-quinovopyranosyl apigenin is described.
Jnanabrata Bhattacharyya, Maria de F. de Oliveira Pires, Leonardo P. Felix, Tania M. S. Silva, George F. Majetich   +4 more
doaj   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Analogs of the Scorpion Venom Peptide Stigmurin: Structural Assessment, Toxicity, and Increased Antimicrobial Activity

Toxins, 2018
Scorpion venom is a rich source of biologically active components and various peptides with high-potential therapeutic use that have been characterized for their antimicrobial and antiproliferative activities.
Adriana M. S. Parente, Alessandra Daniele-Silva, Allanny A. Furtado, Menilla A. Melo, Ariane F. Lacerda, Moacir Queiroz, Cláudia Moreno, Elizabeth Santos, Hugo A. O. Rocha, Euzébio G. Barbosa, Eneas Carvalho, Arnobio A. Silva-Júnior, Marcelo S. Silva, Matheus de F. Fernandes-Pedrosa   +13 more
doaj   +1 more source

Biological Effects of Selenium‐Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder, Alessandro de Souza Prestes, Fernanda D'Avila da Silva, Nilda de Vargas Barbosa, Alix Y. Bastidas Ángel, Mariana F. Soares, Carolina Martins Fernandes, Maria Anttônia Oliveira Petersen, Manuela Moura Silva, Juliete Nathali Scholl, Fabrício Figueiró, Pablo Andrei Nogara, Laura Orian, Eduardo E. Alberto, Michael Ascnher, Diogo Onofre Gomes de Souza, Debora Guerini de Souza, João Batista Teixeira da Rocha   +17 more
wiley   +1 more source

Comprehensive preclinical studies on the bioactivity of Orbignya phalerata Mart. (Babassu) and its derived products: a systematic review

Future Journal of Pharmaceutical Sciences
Background Babassu (Orbignya phalerata Mart.) is a palm tree well distributed in Latin America, whose fruit has a mesocarp and kernel used for human feeding, and empirically related to the treatment of gastritis, vaginitis, and wound healing.
Nicole Debia, Isione Oliveira Castro, Ana Beatriz Santana Sousa, Victor Alves de Oliveira, Helber Alves Negreiros, Paulo Michel Pinheiro Ferreira, João Marcelo de Castro e Sousa   +6 more
doaj   +1 more source

Chemistry and Health: A Multidimensional Approach

Sustainable Chemistry
This review explores both the positive and negative impacts of chemistry on society, focusing on the intersection between pharmaceutical, natural, and synthetic chemicals.
Alcione S. de Carvalho, Iva S. de Jesus, Patrícia G. Ferreira, Acácio S. de Souza, Rafael P. R. F. de Oliveira, Debora O. Futuro, Vitor Francisco Ferreira   +6 more
doaj   +1 more source