Results 41 to 50 of about 1,961 (137)

Targeted delivery of the CB2 receptor agonist JWH‐133 via VCAM‐1‐functionalised nanoparticles attenuates atherosclerosis and reveals sex‐specific therapeutic outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose Atherosclerosis, a chronic inflammatory disease characterised by lipid accumulation and endothelial dysfunction, remains a leading cause of cardiovascular morbidity and mortality. While cannabinoid 2 (CB2) receptor agonists show therapeutic promise in preclinical studies, their systemic application is hindered by poor ...
Lucía Martín‐Navarro, Lucía Martín‐Banderas, Josefa Álvarez‐Fuentes, María Dolores Herrera‐González   +3 more
wiley   +1 more source

Descrição atualizada da paralisia cerebral

Developmental Medicine &Child Neurology, EarlyView.
Resumo A paralisia cerebral (PC) é um termo descritivo amplamente utilizado para um espectro de deficiências motoras causadas por lesão ou malformação cerebral não progressiva ocorrida durante as fases iniciais do desenvolvimento. Avanços recentes nas áreas da genética, de pesquisa em inflamação e em neurofisiologia têm refinado a compreensão ...
Bernard Dan, Peter Rosenbaum, Lucinda Carr, Martin Gough, John Coughlan, Nonyelum Nweke   +5 more
wiley   +1 more source

Caracterização fitoquímica e físico-química das folhas de Bauhinia forficata Link coletada em duas regiões brasileiras

Revista de Ciências Farmacêuticas Básica e Aplicada, 2012
Folhas da espécie vegetal Bauhinia forficata Link, popularmente conhecida como pata de vaca, apresentam amplo potencial terapêutico no tratamento do diabetes mellitus.
Graziella Silvestre Marques, Magaly Andreza Marques Lyra, Monize Santos Peixoto, Rebeka Prisicla Maranhão Monteiro, Waleska Figueirêdo Leão, Haroldo Satiro Xavier, Luiz Alberto Lira Soares, Pedro José Rolim Neto   +7 more
doaj  

Impact of ultraviolet radiation‐induced damage to hair fiber integrity: A multi‐technique physicochemical characterization of surface and cortex properties

International Journal of Cosmetic Science, EarlyView.
UV exposure induces cuticular and cortical damage in natural hair, with oxidative effects and protein degradation comparable to bleaching. However, double bleaching leads to significantly greater structural degradation, emphasizing distinct mechanisms and severity of chemical versus UV‐induced damage. Abstract The combination of chemist techniques is a
Nathana Cindy Barros Silva Ramos, Alzira Xavier Pinto Dini, Viviane Cristina Albarici, Mayara Miranda Ferreira, Caroline Vieira Hercolino, Adriano da Silva Pinheiro, André Rolim Baby, Maria Valéria Robles Velasco   +7 more
wiley   +1 more source

Role of Polymeric Excipients in the Stabilization of Olanzapine when Exposed to Aqueous Environments

Molecules, 2015
Hydrate formation is a phase transition which can occur during manufacturing processes involving water. This work considers the prevention of hydration of anhydrous olanzapine and hydrate conversions in the presence of water and polymers ...
Maria Paisana, Martin Wahl, João Pinto
doaj   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

International Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota, Klaus Kümmerer, Isabel Martins de Almeida, Emília Sousa   +3 more
wiley   +1 more source

Burchellin: study of bioactivity against Aedes aegypti

Parasites & Vectors, 2014
Background The dengue mosquito Aedes aegypti Linnaeus, 1762 is a widespread insect pest of serious medical importance. Since no effective vaccine is available for treating dengue, the eradication or control of the main mosquito vector is regarded as ...
Juliana Oliveira Abreu Narciso, Renata Oliveira de Araújo Soares, Jacenir Reis dos Santos Mallet, Anthony Érico Guimarães, Maria Célia de Oliveira Chaves, José Maria Barbosa-Filho, Marise Maleck   +6 more
doaj   +1 more source

Editorial: A Assistência Farmacêutica como direito a preservar

Jornal de Assistência Farmacêutica e Farmacoeconomia, 2022
No período recente, que vai de 2003 a meados de 2016, o Ministério da Saúde criou, em sua estrutura, uma Secretaria de Ciência, Tecnologia e Insumos Estratégicos (SCTIE) e, ligado a ela, um Departamento de Assistência Farmacêutica e Insumos Estratégicos
José Miguel do Nascimento Júnior
doaj   +1 more source

Sharing the Burden: The Impacts of Pharmacy Sector Reforms on the Labor Market for Pharmacists in Portugal

Industrial Relations: A Journal of Economy and Society, EarlyView.
ABSTRACT During the 2010 crisis, the Portuguese government enacted several reforms to its prescription drug reimbursement system. As a result, value added per pharmacist in pharmacies fell by a third. We use longitudinal records from Quadros de Pessoal (QP), merged with collective bargaining data and firm financial records, to study the impacts of the ...
David Card, Ana Rute Cardoso, Pedro Luis Silva   +2 more
wiley   +1 more source

Histopathological and Molecular Data on Myxobolus spp. Infecting Bryconid Fish From the Brazilian Pantanal Wetland

Journal of Fish Diseases, EarlyView.
ABSTRACT Previous studies described Myxobolus umidus infecting the spleen of Brycon hilarii, whereas Myxobolus pantanalis and Myxobolus salminus infecting the gill filaments of Salminus brasiliensis. In this study, we provided supplementary morphological and molecular data on these three Myxobolus species and histopathological analyses of the tissues ...
Caroline Munhoz Meira, Milena Lucia Cornejo, Sarah Arana, Edson Aparecido Adriano, Antonio Augusto Mendes Maia   +4 more
wiley   +1 more source