Results 41 to 50 of about 39,192 (187)

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Módulo 7 - Tópicos especiais em ética, avaliação de tecnologias em saúde e aspectos técnicos e legais relacionados aos medicamentos alopáticos [PDF]

, 2016
O Módulo está organizado em três unidades de aprendizagem: Ética e medicalização, Avaliação econômica de tecnologias em saúde e Estudos dos aspectos técnicos e legais relacionados aos medicamentos e seus impactos na assistência farmacêutica.
Farias, Mareni Rocha, Peres, Kaite Cristiane, Pupo, Guilherme Daniel, Santos, Rosana Isabel dos   +3 more
core  

Isolation and Characterization of the ‘Flavonoid Crystals’ of Three Species of : Chemotaxonomic Considerations of the Genera and

Natural Product Communications, 2007
The isolation of fragnettin, the so called ‘flavonoid crystals’, from three species of Prosthechea , namely P. fragrans, P. vespa and P. caetensis , and its characterization as 8- C -β-D-quinovopyranosyl apigenin is described.
Jnanabrata Bhattacharyya, Maria de F. de Oliveira Pires, Leonardo P. Felix, Tania M. S. Silva, George F. Majetich   +4 more
doaj   +1 more source

Analogs of the Scorpion Venom Peptide Stigmurin: Structural Assessment, Toxicity, and Increased Antimicrobial Activity

Toxins, 2018
Scorpion venom is a rich source of biologically active components and various peptides with high-potential therapeutic use that have been characterized for their antimicrobial and antiproliferative activities.
Adriana M. S. Parente, Alessandra Daniele-Silva, Allanny A. Furtado, Menilla A. Melo, Ariane F. Lacerda, Moacir Queiroz, Cláudia Moreno, Elizabeth Santos, Hugo A. O. Rocha, Euzébio G. Barbosa, Eneas Carvalho, Arnobio A. Silva-Júnior, Marcelo S. Silva, Matheus de F. Fernandes-Pedrosa   +13 more
doaj   +1 more source

Descrição atualizada da paralisia cerebral

Developmental Medicine &Child Neurology, EarlyView.
Resumo A paralisia cerebral (PC) é um termo descritivo amplamente utilizado para um espectro de deficiências motoras causadas por lesão ou malformação cerebral não progressiva ocorrida durante as fases iniciais do desenvolvimento. Avanços recentes nas áreas da genética, de pesquisa em inflamação e em neurofisiologia têm refinado a compreensão ...
Bernard Dan, Peter Rosenbaum, Lucinda Carr, Martin Gough, John Coughlan, Nonyelum Nweke   +5 more
wiley   +1 more source

The lichen family Cladoniaceae in Paraiba, Pernambuco and Sergipe, Northeast Brazil [PDF]

, 1993
Field and herbarium studies of the lichen family Cladoniaceae in the states of Paraíba, Pernambuco and Sergipe, Northeast Brazil, yielded 22 species, many of them being new reports for the region.
Ahti, Teuvo, Filho, Lauro Xavier, Stenroos, Soili   +2 more
core  

Comprehensive preclinical studies on the bioactivity of Orbignya phalerata Mart. (Babassu) and its derived products: a systematic review

Future Journal of Pharmaceutical Sciences
Background Babassu (Orbignya phalerata Mart.) is a palm tree well distributed in Latin America, whose fruit has a mesocarp and kernel used for human feeding, and empirically related to the treatment of gastritis, vaginitis, and wound healing.
Nicole Debia, Isione Oliveira Castro, Ana Beatriz Santana Sousa, Victor Alves de Oliveira, Helber Alves Negreiros, Paulo Michel Pinheiro Ferreira, João Marcelo de Castro e Sousa   +6 more
doaj   +1 more source

Chemistry and Health: A Multidimensional Approach

Sustainable Chemistry
This review explores both the positive and negative impacts of chemistry on society, focusing on the intersection between pharmaceutical, natural, and synthetic chemicals.
Alcione S. de Carvalho, Iva S. de Jesus, Patrícia G. Ferreira, Acácio S. de Souza, Rafael P. R. F. de Oliveira, Debora O. Futuro, Vitor Francisco Ferreira   +6 more
doaj   +1 more source

Impact of ultraviolet radiation‐induced damage to hair fiber integrity: A multi‐technique physicochemical characterization of surface and cortex properties

International Journal of Cosmetic Science, EarlyView.
UV exposure induces cuticular and cortical damage in natural hair, with oxidative effects and protein degradation comparable to bleaching. However, double bleaching leads to significantly greater structural degradation, emphasizing distinct mechanisms and severity of chemical versus UV‐induced damage. Abstract The combination of chemist techniques is a
Nathana Cindy Barros Silva Ramos, Alzira Xavier Pinto Dini, Viviane Cristina Albarici, Mayara Miranda Ferreira, Caroline Vieira Hercolino, Adriano da Silva Pinheiro, André Rolim Baby, Maria Valéria Robles Velasco   +7 more
wiley   +1 more source

Role of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on immediate implant placement in type 2 diabetic rats

Photochemistry and Photobiology, EarlyView.
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin, Carolina Sayuri Wajima, Fábio Roberto de Souza Batista, Naara Gabriela Monteiro, Isadora Castaldi Sousa, Valdir Gouveia Garcia, Dóris Hissako Matsushita, Letícia Helena Theodoro, Roberta Okamoto   +8 more
wiley   +1 more source