Results 31 to 40 of about 13,950 (151)

Prevalence of Meningitis Among Neonates With Sepsis: Analysis of Predictors at a Tertiary Care Hospital in Bangladesh

Reproductive, Female and Child Health, Volume 5, Issue 1, March 2026.
ABSTRACT Objective To identify the prevalence of neonatal meningitis and to describe the clinical, haematological and bacteriological profiles of neonatal sepsis and meningitis. This study also aimed to identify the factors predictive of meningitis among neonates with sepsis.
Syeda Humaida Hasan, Humayra Akter, Jagadish C. Das, Adrita Das   +3 more
wiley   +1 more source

Comparative renal safety of teicoplanin versus vancomycin in older patients: a propensity-matched multicenter study

International Journal of Infectious Diseases
Objectives: To compare nephrotoxicity between teicoplanin and vancomycin in older patients, investigate the correlation between teicoplanin average steady-state trough concentrations (Cmin,ss) and nephrotoxicity, and identify independent risk factors for
Jionghe Wu, Tingting Liu, Peng Na, Yaping Yuan, Xia Wu, Chao Wang, Zhimei Duan, Jing Zhao, Yu Zhou, Xiangqun Fang, Lixin Xie, Hongxia Li   +11 more
doaj   +1 more source

Local Versus Systemic Antibiotics for Diabetic Foot Infection—A Systematic Review and Meta‐Analysis

Journal of Diabetes, Volume 18, Issue 3, March 2026.
Combined local and systemic antibiotic therapy improved clinical cure rates and shortened healing time in diabetic foot infections compared with systemic therapy alone. However, due to the low quality of existing studies, high‐quality randomized controlled trials are needed to confirm these findings. ABSTRACT Diabetic foot infection (DFI) includes soft
Anas Khan, Hester Lacey, Helena Michels, Mohamed Elahwal, Bjorn Telgenkamp   +4 more
wiley   +1 more source

An investigation into the correlation between intraperitoneal teicoplanin concentrations and treatment outcomes in peritoneal dialysis-associated peritonitis

Frontiers in Pharmacology
Peritoneal dialysis-associated peritonitis (PDAP) is a frequent complication of peritoneal dialysis. The guidelines from the International Society for Peritoneal Dialysis (ISPD) suggest administering teicoplanin through the peritoneal route to treat PDAP,
Lulu Wang, Lulu Wang, Jiangqing Fan, Xuejie Chen, Wenpu Lei, Chunming Jiang, Hang Liu, Yun Yang, Jizhong Shen   +8 more
doaj   +1 more source

A Bifunctional Cytochrome P450 Enzyme Catalyzes Hydroxylation and Aryl‐Aryl Ether Formation in the Biosynthesis of Emestrin

Chemistry – A European Journal, Volume 32, Issue 7, 16 February 2026.
Conversion of emestrin J (5) to emestrin (1) by three P450 enzymes from the cluster (eme) in Emericella quadrilineata. EmeO acts as a bifunctional enzyme for the construction of the 15‐membered lactone ring via an aryl‐aryl ether bond formation and simultaneous hydroxylation between phenolic and nonphenolic aromatic rings, while EmeE and EmeR install ...
Yu‐Chuan Chen, Jing‐Jing Wu, Ming‐Hua Chen, Shu‐Ming Li   +3 more
wiley   +1 more source

A Highly Efficient Fluorescent Turn-Off Nanosensor for Quantitative Detection of Teicoplanin Antibiotic from Humans, Food, and Water Based on the Electron Transfer between Imprinted Quantum Dots and the Five-Membered Cyclic Boronate Esters

Molecules
Teicoplanin has been banned in the veterinary field due to the drug resistance of antibiotics. However, teicoplanin residue from the antibiotic abuse of humans and animals poses a threat to people’s health.
Yansong Zhang, Daojin Li, Xiping Tian
doaj   +1 more source

Glycopeptide Antibiotics: Structural and Functional Aspects, Human Medicinal Use, and Standardisation

Регуляторные исследования и экспертиза лекарственных средств, 2023
In recent years, glycopeptide antibiotics have been widely used to treat severe bacterial infections. The long-term use of first-generation antibiotics of this group (vancomycin, teicoplanin) has contributed to the emergence of bacteria resistant to them.
O. N. Vysochanskaya, S. I. Kuleshova, E. P. Simonova   +2 more
doaj   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Clinical efficacy of teicoplanin combined with L-carnitine for methicillin-resistant Staphylococcus aureus infective endocarditis

Di-san junyi daxue xuebao, 2020
Objective To observe the clinical efficacy of teicoplanin combined with levocarnitine in treatment of methicillin-resistant Staphylococcus aureus (MRSA) infective endocarditis (IE). Methods A total of 84 patients diagnosed with IE caused by MRSA admitted
JIANG Ximeng, TIAN Donghua, WANG Xiaoli, ZHANG Jinying   +3 more
doaj   +1 more source

Extensive Intracerebral Hemorrhage Involving Basal Ganglia and Frontal Lobe With Intraventricular and Subarachnoid Extension in a Triplet Pregnancy Following In Vitro Fertilization: A Case Report and Review

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Triplet births, particularly those achieved by assisted reproductive technologies, entail markedly elevated maternal and fetal risks, including hypertensive diseases. Intracerebral hemorrhage is an uncommon but devastating complication during the postpartum period.
Raman Goit, Prakash Gupta, Linh Nguyen, Shachi Patel, Karankumar Rana, Suman Jaiswal, Prateeti Bekoju, Ranju Shrestha, Daniel Nguyen   +8 more
wiley   +1 more source