Mice carrying the homologous human shelterin POT1-L259S mutation linked to pulmonary fibrosis show a telomerase deficiency-like phenotype with telomere shortening with increasing mouse generations. [PDF]
Sánchez-Vázquez R +5 more
europepmc +1 more source
Mechanisms of enhancer‐driven oncogene activation
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend +2 more
wiley +1 more source
Correction: Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. [PDF]
Al-Dulaimi S +3 more
europepmc +1 more source
Structure of stem-loop IV of Tetrahymena telomerase RNA
Yu Chen +5 more
openalex +1 more source
Telomere Length Abnormality: Investigating Approaches and Correlations with Cancer, Bone Marrow Failure and Hematological Malignancies. [PDF]
Tarella C +7 more
europepmc +1 more source
New Insights into Lymphocyte Differentiation and Aging from Telomere Length and Telomerase Activity Measurements [PDF]
Tinhinane Fali +6 more
openalex +1 more source
Oxidative Stress-Telomere Axis in IVF: Molecular Mechanisms, Biomarkers, and Clinical Translation. [PDF]
Voros C +19 more
europepmc +1 more source

