Results 181 to 190 of about 85,495 (318)
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Advances on telomere length in relation to sleep disorders and cell senescence
Chinese Journal of Contemporary Neurology and Neurosurgery, 2019 Telomere is a special curved cap-like structure at the end of the linear chromosome of eukaryotic cells. It is a nuclear protein complex composed of DNA repeat sequences containing TTAGGG and telomere-binding proteins.
Pei-pei LIU, Mei ZHANG
doaj
Telomere Length, Telomere-binding Proteins, and DNA Damage Signaling
Cold Spring Harbor Symposia on Quantitative Biology, 2000 M T, Hemann +3 more
openaire +2 more sources
Technologies for engineering repetitive DNA
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley +1 more source
Arabidopsis thaliana telomeric DNA-binding protein 1 is required for telomere length homeostasis and its Myb-extension domain stabilizes plant telomeric DNA binding [PDF]
, 2007 Moo Gak Hwang, Myeon Haeng Cho
openalex +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
MedComm – Oncology, Volume 5, Issue 2, June 2026.Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles. [PDF]
Aging (Albany NY)Ruano JL +6 more
europepmc +1 more source
Journal of Internal Medicine, Volume 299, Issue 6, Page 694-710, June 2026.Abstract Alzheimer's disease (AD) is neuropathologically defined by amyloid‐beta (Aβ) plaques and tau neurofibrillary tangles. However, co‐pathologies and other pathobiological processes are involved in the pathogenesis of AD, contributing to neurodegeneration and clinical symptoms.
Daniel Ferreira +9 more
wiley +1 more source