Enterovirus 71 3C Promotes Apoptosis through Cleavage of PinX1, a Telomere Binding Protein. [PDF]
Li J +7 more
europepmc +1 more source
Coordinate regulation between expression levels of telomere‐binding proteins and telomere length in breast carcinomas [PDF]
Kimberly S. Butler +3 more
openalex +1 more source
Structure and sequence evolution in the pennycress (Thlaspi arvense) pangenome
Summary Eukaryotic genomes harbor many forms of variation, including nucleotide diversity and structural polymorphisms, which experience natural selection and contribute to genome evolution and biodiversity. Harnessing this variation for agriculture hinges on our ability to detect, quantify, catalog, and deploy genetic diversity. Here, we explore seven
Kevin A. Bird +25 more
wiley +1 more source
Characterizing telomere-binding protein Hmbox1a/b and Zbtb48 in zebrafish
Telomeres are nucleoprotein structures at the ends of linear chromosomes, bound by various proteins. Some of these proteins protect the telomere ends, such as the shelterin complex, while others help regulate telomere length. Recently, our lab has characterized two telomere-binding proteins, HMBOX1 and ZBTB48, in mammalian cell lines.
openaire +2 more sources
Regulated Cell Death in Idiopathic Pulmonary Fibrosis
This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan +10 more
wiley +1 more source
Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation [PDF]
Wolfgang Hiddemann +4 more
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Guardians of the Genome: How the Single-Stranded DNA-Binding Proteins RPA and CST Facilitate Telomere Replication [PDF]
Conner L. Olson, Deborah S. Wuttke
openalex +1 more source

