Mice carrying the homologous human shelterin POT1-L259S mutation linked to pulmonary fibrosis show a telomerase deficiency-like phenotype with telomere shortening with increasing mouse generations. [PDF]
Sánchez-Vázquez R +5 more
europepmc +1 more source
Methylation of the telomerase gene promoter region in umbilical cord blood of patients with gestational diabetes mellitus is associated with decreased telomerase expression levels and shortened telomere length [PDF]
Shuhua Liu +6 more
openalex +1 more source
Teruzo Asahara, Hidehiro Okazaki
openaire +2 more sources
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Infection-Induced Telomere Length Variation: Insights into Pathogenesis of Koala Retrovirus. [PDF]
Cheung HM +5 more
europepmc +1 more source
Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa +11 more
wiley +1 more source
Parental Age Effects on Offspring Telomere Length Across Vertebrates: A Meta-Analysis. [PDF]
Vlasova M, Sun Y, Chik HYJ, Dugdale HL.
europepmc +1 more source
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė +10 more
wiley +1 more source

