Results 211 to 220 of about 89,702 (246)

Assessment of mosaic loss of chromosome Y in pulmonary fibrosis reveals limited association with susceptibility or disease severity. [PDF]

open access: yesBMJ Open Respir Res
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Telomere telomere recombination provides an express pathway for telomere acquisition

Nature, 1990
DNA termini from Tetrahymena and Oxytricha, which bear C4A2 and C4A4 repeats respectively, can support telomere formation in Saccharomyces cerevisiae by serving as substrates for the addition of yeast telomeric C1-3A repeats. Previously, we showed that linear plasmids with 108 base pairs of C4A4 DNA (YLp108CA) efficiently acquired telomeres, whereas ...
S S, Wang, V A, Zakian
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Telomeres

Experimental Gerontology, 2006
The role that telomere biology may play in the human ageing process is of a significant interest to many laboratories around the world. In this, the first of a series of yearly reviews on telomeres and ageing, I review a small selection of papers published between July 2005 and June 2006 that maybe of direct relevance to the gerontology research ...
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Telomeric noncoding RNA: telomeric repeat‐containing RNA in telomere biology

WIREs RNA, 2014
AbstractTelomeres are nucleoprotein structures that cap the ends of eukaryotic chromosomes, protecting them from degradation and activation of DNA damage response. For this reason, functional telomeres are vital to genome stability. For years, telomeres were assumed to be transcriptionally silent, because of their heterochromatic state.
Cusanelli, Emilio, Chartrand, Pascal
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Telomeres

Current Opinion in Cell Biology, 1991
Telomeres are essential for chromosome stability and replication. Maintaining a balance between telomere shortening and lengthening is essential for cell viability. Recent work on telomeres from yeast, Drosophila and mammals, and on telomerase has provided insight into the mechanisms of both the shortening and lengthening processes.
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