Results 181 to 190 of about 110,609 (302)

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Parental Age Effects on Offspring Telomere Length Across Vertebrates: A Meta-Analysis. [PDF]

Mol Ecol
Vlasova M, Sun Y, Chik HYJ, Dugdale HL.
europepmc   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 859-871, April 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Infection and telomere length: A systematic review. [PDF]

PLoS One
Tunnicliffe L, Muzambi R, Bartlett JW, Howe LD, Basit KA, Asare K, Gore-Langton G, Mansfield KE, Codd V, Warren-Gash C.   +9 more
europepmc   +1 more source

Preoperative Detection of Dual TERT Promoter Mutations in Thyroid Cancer: A Case Series

Diagnostic Cytopathology, Volume 54, Issue 4, Page E108-E112, April 2026.
ABSTRACT Telomerase reverse transcriptase promoter (TERTp) mutations are associated with aggressive thyroid cancer and are most frequently found in anaplastic and poorly differentiated thyroid cancer. Pre‐operative thyroid nodule molecular testing can detect TERTp, denoting a high risk of malignancy and possible aggressive clinical features such as ...
Amir Harari, Jennifer Huiras, Yang Chen, Mohammed Alshalalfa, Yangyang Hao, Joshua P. Klopper, Richard T. Kloos, Bianca J. Vazquez   +7 more
wiley   +1 more source

Leukocyte Telomere Length Variants Are Independently Associated with Survival of Patients with Colorectal Cancer. [PDF]

Cancers (Basel)
Sarkar G, Chen J, Sood S, Fischer K, Kossick K, Schupack D, Graham R, Druliner B, Heydari Z, Helgeson L, Cruz Garcia E, Cawthon R, Boardman L.   +12 more
europepmc   +1 more source

Brain Age Estimation on T2‐FLAIR Scans for Application to Multiple Sclerosis

Human Brain Mapping, Volume 47, Issue 5, 1 April 2026.
While the brain‐age paradigm has emerged as a promising biomarker of neurodegeneration in multiple sclerosis (MS), most available brain‐age prediction models are based on 3D‐T1w scans, which are not acquired in routine clinical practice. Leveraging a large multicentre collection of scans from healthy controls, we developed an accurate brain‐age ...
Jordan Colman, Giuseppe Pontillo, Olivia Goodkin, Michael A. Foster, Nima Mahmoudi, Mike P. Wattjes, Arturo Brunetti, Gabriel Gonzalez‐Escamilla, Sergiu Groppa, Einar August Høgestøl, Lars T. Westlye, Silvia Messina, Jacqueline Palace, Rosa Cortese, Nicola De Stefano, Àlex Rovira, Jaume Sastre‐Garriga, Stefan Ropele, Christian Enzinger, Maria A. Rocca, Massimo Filippi, Barbara Bellenberg, Carsten Lukas, Massimiliano Calabrese, Marco Castellaro, Tomas Uher, Manuela Vaneckova, Ahmed Toosy, Olga Ciccarelli, Tarek Yousry, Ferran Prados, Frederik Barkhof, James H. Cole, MAGNIMS Study Group, Frederik Barkhof, Nicola de Stefano, Jaume Sastre‐Garriga, Olga Ciccarelli, Christian Enzinger, Massimo Filippi, Claudio Gasperini, Cristina Granziera, Gabriele Deluca, Menno M. Schoonheim, Alex Rovira, Maria A. Rocca, Ahmed Toosy   +46 more
wiley   +1 more source

Leukocyte telomere length and circulating MiRNAs in relation to cardiovascular outcomes in older adults. [PDF]

BMC Geriatr
La Grotta R, Crocco P, Leonova A, Cosimo SC, Morelli F, Dato S, Passarino G, Rose G.   +7 more
europepmc   +1 more source

New perspectives on the physiological basis of muscle loss

Experimental Physiology, EarlyView.
Alistair J. Monteyne, Marlou L. Dirks
wiley   +1 more source