Results 201 to 210 of about 110,609 (302)

Reply to Cooper and Stanojevic: ‘Is lung function in a race against time?’

Experimental Physiology, EarlyView.
Samuel Wallbanks
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, Volume 13, Issue 14, 9 March 2026.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Methods for telomere length measurement: an update on current technologies and emerging approaches. [PDF]

Front Mol Biosci
Makarova JA, Belova UD, Zvereva MI, Shkurnikov MY, Tonevitsky AG.   +4 more
europepmc   +1 more source

Telomere measurement tools: Telometric produces biased estimates of telomere length [PDF]

, 2011
H M Salomons, HM Salomons, JD Grant, M F Haussmann, MF Haussmann, P Monaghan, S Verhulst, T Horn   +7 more
core   +2 more sources

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, Volume 13, Issue 13, 3 March 2026.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

Telomere length, aging, and cognitive function in the Midwestern Amish. [PDF]

HGG Adv
Liu Y, Song YE, Lynn A, Wang W, Miskimen K, Fuzzell SL, Hochstetler SD, Laux RA, Caywood LJ, Clouse JE, Herington SD, Wang P, Gulyayev A, Dorfsman DA, Moore NC, Main LR, Prough MB, Zaman AF, Adams LD, Whitehead P, Ogrocki P, Lerner AJ, Vance JM, Cuccaro ML, Scott WK, Pericak-Vance MA, Haines JL.   +26 more
europepmc   +1 more source

Time‐Efficient and Informatic‐Skill‐Light Gap‐Filling for Telomere‐to‐Telomere Genome Assembly

Advanced Science, Volume 13, Issue 14, 9 March 2026.
The paper introduces a novel auxiliary software toolbox GapSuite, consisting of two tools Gap‐Aid and Gap‐Graph, which guides users to fill gaps in chromosome‐level genome assembly using sequence‐extension‐based and assembly‐graph‐based strategies. The two tools enable users with limited informatics expertise to efficiently complete gap‐filling on ...
Dong Xu, Xianjia Zhao, Lianguang Shang, Shaolong Tian, Yanchun Li, Huaming Wen, Qiang Xu, Dongxi Li, Weihua Pan   +8 more
wiley   +1 more source

Investigation of the Telomere Length in PERI-Implant Oral Mucosa Cells. [PDF]

J Oral Pathol Med
Giffoni FC, Gomes TEC, de Souza PN, Silva PVE, Magno LAV, Cândido AL, Lasmar MF, de Oliveira Neto SG, Ferreira MVL, Araujo TMG, Dos Santos LI, Chrcanovic BR, Gomez RS, Martins-Chaves RR.   +13 more
europepmc   +1 more source

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu, Ju‐Chan Park, Heesoo Uhm, Yong‐Woo Kim, Hyeon Woo Im, Sangsu Bae   +5 more
wiley   +1 more source

Plasma Proteome Signature for Leukocyte Telomere Length and Its Link to Abdominal Aortic Aneurysm. [PDF]

J Cell Mol Med
Li A, Austin TR, Steffen BT, Jacobson I, Xie J, Pankratz N, Lane JA, Fitzpatrick A, Bis JC, Arking DE, Mosley T, Sedaghat S, Pankow JS, Lutsey PL, Guan W, Tang W.   +15 more
europepmc   +1 more source