Results 211 to 220 of about 110,609 (302)

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Increased dairy product consumption is associated with shorter telomere length in buccal cells among normotensive adults. [PDF]

Biomedicine (Taipei)
Tsai HH, Su YD, Lai ZL, Lin CY, Lin SF, Hsu HC, Lin WY, Hsueh PR.   +7 more
europepmc   +1 more source

New Insights Into Changes in the DNA Methylation Pattern of the SHOX Gene in Patients With Léri‐Weill Dyschondrosteosis

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 606-618, March 2026.
ABSTRACT SHOX gene haploinsufficiency is associated with Léri‐Weill dyschondrosteosis (LWD) or idiopathic short stature (ISS) and could be caused by the structural and point mutations in the coding region and by the deletions in SHOX gene regulatory sequences. The role of the duplications in regulatory sequences is ambivalent.
Valeriia Kopytko, Katerina Hirschfeldova, Pavlina Capkova, Roman Solc   +3 more
wiley   +1 more source

Herpesvirus genome integration in whole‐genome sequences of dementia and control cohorts

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The infectious hypothesis suggests that microbes like herpesviruses may play a role in the pathogenesis of Alzheimer's disease (AD) and other related dementias through methods that may include viral genome integration. The occurrence of herpesvirus genome integration in dementia patients has not been thoroughly characterized ...
Stacey L. Piotrowski, Mary Alice Allnutt, Kory Johnson, Toshiko Tanaka, Luigi Ferrucci, Huw Morris, John Hardy, PROSPECT Consortium, Mina Ryten, United Kingdom Brain Expression Consortium (UKBEC), Giancarlo Logroscino, Juan Troncoso, Thomas G. Beach, Geidy E. Serrano, Carlos Cruchaga, Dennis W. Dickson, Owen A. Ross, Adriano Chiò, International LBD Genomics Consortium, International ALS Genomics Consortium, Henry Houlden, The American Genome Center, Clifton L. Dalgard, Jinhui Ding, J. Raphael Gibbs, Bryan J. Traynor, Sonja W. Scholz, Steven Jacobson   +27 more
wiley   +1 more source

Grandmother Age Effects via Sperm Telomere Length and Egg Telomerase Transcripts. [PDF]

Mol Ecol
Kim SY, Chiara V, Velando A.
europepmc   +1 more source

CRISPR Assays for Protein Detection

Chemistry–Methods, Volume 6, Issue 3, March 2026.
This review summarizes recent advances in CRISPR–Cas–based strategies for protein detection. Particular focus is placed on recognition element–based approaches, in which antibodies, aptamers, or DNAzymes convert protein binding into CRISPR‐readable nucleic acid signals, and activity‐based strategies that exploit intrinsic protein functions to trigger ...
Luca Capelli, Elena Spezzani, Dharshini Raghavan, Chiara Micucci, Alessandra Zanut, Alessandro Bertucci   +5 more
wiley   +1 more source

Infection-Induced Telomere Length Variation: Insights into Pathogenesis of Koala Retrovirus. [PDF]

Viruses
Cheung HM, Lin SWJ, Nguyen HTH, Stephenson T, Speight N, Hemmatzadeh F.   +5 more
europepmc   +1 more source

Genomic Integrity in Gull Chicks Predicts Colony Departure and Postfledging Movements

Ecology and Evolution, Volume 16, Issue 3, March 2026.
We integrated molecular biomarkers with high‐resolution GPS tracking to study key behavioral decisions during the transition to independence in a long‐lived colonial seabird. We found that juveniles with shorter telomeres and higher DNA damage leave the colony earlier, revealing a link between physiological state and movement ecology.
Alberto Velando, Susana Cortés‐Manzaneque, Sin‐Yeon Kim   +2 more
wiley   +1 more source

A high-throughput method for quantifying relative telomere length in single cells in situ combined with live-cell imaging. [PDF]

J Mol Cell Biol
Sun Q, Zou Z, Min M.
europepmc   +1 more source

Artificial Intelligence and Prostate–Breast Cancer Biology: Recent Advances in Treatments and Perspectives — A Comprehensive Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims The therapeutic limitations of conventional cancer treatment currently deployed are driving the development and creation of new nano‐drugs. Prostate cancer (PCa) is a prevalent clinical problem in older men with a significant global incidence, with 1.5 million cases reported in 2022.
Russell B. O. Ouma, Silas M. Ngari, Joshua K. Kibet   +2 more
wiley   +1 more source