Results 231 to 240 of about 57,502 (259)
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Childhood Adversity and Telomere Length
Biological Research For NursingPurpose: Exposure to adversity during childhood and adolescence is associated with numerous health conditions in adulthood; telomere shortening may be a mechanism through which adversity contributes to poor outcomes. We studied three areas of adversity (parent relational instability, child household instability, and financial instability) occurring ...
Rita H. Pickler +5 more
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Telomere length in Hepatitis C
Cancer Genetics and Cytogenetics, 2008Telomeres are nucleoprotein structures located at the termini of chromosomes that protect the chromosomes from fusion and degradation. Hepatocyte cell-cycle turnover may be a primary mechanism of telomere shortening in hepatitis C virus (HCV) infection, inducing fibrosis and cellular senescence. HCV infection has been recognized as potential cause of B-
Y, Kitay-Cohen +4 more
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Diet, nutrition and telomere length
The Journal of Nutritional Biochemistry, 2011The ends of human chromosomes are protected by DNA-protein complexes termed telomeres, which prevent the chromosomes from fusing with each other and from being recognized as a double-strand break by DNA repair proteins. Due to the incomplete replication of linear chromosomes by DNA polymerase, telomeric DNA shortens with repeated cell divisions until ...
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Haploinsufficiency and telomere length homeostasis
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2012In humans, autosomal dominant or X-linked disease can arise through a phenomenon termed haploinsufficiency, where one remaining wild-type allele is insufficient for function. In model organisms, the impact of heterozygosity can be tested directly with engineered mutant alleles or in a hemizygous state where the expression of one allele is abrogated ...
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Fatty acids and telomere length
Current Opinion in Clinical Nutrition & Metabolic CarePurpose of review This narrative review includes the latest clinical and preclinical evidence on fatty acid exposure and telomere length, a widely accepted hallmark of aging. Recent findings A large body of literature focused on n-3 (omega-3) polyunsaturated fatty acids (PUFAs ...
Marta, Crous-Bou +3 more
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Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Science, 2020Renhong Yan, Yuanyuan Zhang, Yaning Li
exaly
Materials design for bone-tissue engineering
Nature Reviews Materials, 2020Mani Diba, Antonios G Mikos
exaly
Telomere Length and Clonal Hematopoiesis
New England Journal of Medicine, 2023openaire +2 more sources