Results 281 to 290 of about 114,134 (356)

Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi, Azadeh Niknejad, Elaheh Amini   +2 more
wiley   +1 more source

NPM1 phosphorylation-mediated telomere maintenance via stabilization of POLD3 in ALT-positive osteosarcoma: unraveling mechanisms and therapeutic opportunities. [PDF]

Theranostics
Zhao R, Li T, Yang Q, Jiang D, Xue Y, Kou H, Wang Q, Wang Y, Han X, Ma W, Wang G, Feng J, Han X, Liu Y, Jing Y, Geng X, Wang F, Liu Y, Zhang Q, Wang F.   +19 more
europepmc   +1 more source

The physiology of survival: Space

Experimental Physiology, EarlyView.
Damian M. Bailey, Angelique van Ombergen
wiley   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Telomere shortening in laminopathic dilated cardiomyopathy. [PDF]

NPJ Regen Med
Chang ACY, Pardon G, Chang ACH, Wang C, Termglinchan V, Kirillova A, Nicin L, Birnbaum F, Laquerrière A, Bonne G, Wu J, Blau HM.   +11 more
europepmc   +1 more source

Highly heterozygous Citrus changshan‐huyou Y. B. Chang originated from ancient hybridization between mandarin and pummelo and displayed distinct tissue‐specific allelic imbalance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract The genus Citrus is characterized by a reticulate evolutionary history with frequent hybridization, making it an intriguing subject for genome evolution investigation. Citrus changshan‐huyou Y. B. Chang (Huyou) is a unique landrace first discovered in Zhejiang Province, China, with premium fruit quality.
Zhanghui Zeng, Yingjie Luo, Haifei Hu, Lan Lan, Baojin Guo, Ping Zhou, Cong Tan, Xiaoping Huang, Tuo Qi, Zhehao Chen, Zhiming Yu, Lilin Wang, Taihe Xiang, Chengdao Li, Yong Jia   +14 more
wiley   +1 more source

Molecular Mechanisms of Accelerated Ageing in Geriatric Depression: Interplay of Telomere Attrition, Mitochondrial Dysfunction and Cellular Senescence. [PDF]

Int J Mol Sci
Revi Shanker P, Dorajoo R.
europepmc   +1 more source

PAX8‐positive conventional urothelial carcinomas of the urinary bladder and their distinct molecular profiles – A clinicopathologic study of 101 consecutive cases with next‐generation sequencing in 20 cases

Histopathology, Volume 88, Issue 7, Page 1315-1323, June 2026.
PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert, Wendy Luo, Allen C Zhu, Peng Wang, Tatjana Antic, Jung Woo Kwon   +5 more
wiley   +1 more source

Chromosomal Instability and Telomere Attrition in Systemic Sclerosis: A Historical Perspective. [PDF]

Genes (Basel)
Artlett CM.
europepmc   +1 more source

Don't Cut the Cord: Why Umbilical Cord Blood Still Deserves a Place in Transplantation

International Journal of Immunogenetics, Volume 53, Issue 3, Page 229-239, June 2026.
ABSTRACT The use of umbilical cord blood (UCB) as a stem cell source in haematopoietic stem cell transplant (HSCT) has greatly declined in recent years. It has largely been replaced by mismatched unrelated and family donors, facilitated by advances in transplant technologies, including post‐transplant cyclophosphamide to prevent graft‐versus‐host ...
Jenna Nunn, Kay Poulton, Robert Wynn
wiley   +1 more source