Mice carrying the homologous human shelterin POT1-L259S mutation linked to pulmonary fibrosis show a telomerase deficiency-like phenotype with telomere shortening with increasing mouse generations. [PDF]
Genes DevSánchez-Vázquez R +5 more
europepmc +1 more source
Telomere structure and telomerase in health and disease
, 2012 Daniel E. Gómez +6 more
openalex +2 more sources
Early adversity and the comorbidity between metabolic disease and psychopathology
The Journal of Physiology, EarlyView.Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Control of telomerase recruitment and end protection by independent shelterin components. [PDF]
Nat CommunSandhu R +4 more
europepmc +1 more source
No Correlation Between Childhood Maltreatment and Telomere Length
, 2010 Daniel Glass +4 more
openalex +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
The Journal of Physiology, EarlyView.Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Hematological complications in solid organ transplant recipients with telomere biology disorders: a narrative review. [PDF]
Front ImmunolCarlier FM +6 more
europepmc +1 more source
Malaria infection and telomere length: A review
Theophilus Nang Wakai +4 more
openalex +1 more source
Intramuscular pathways of maladaptation in overtraining syndrome
The Journal of Physiology, EarlyView.Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
A role for WRN in telomere-based DNA damage responses
, 2006 Mark S. Eller +7 more
openalex +1 more source