Results 171 to 180 of about 70,369 (254)

Radiation Effects on Normal Brain in Subjects With Recurrent Glioblastoma by Spectroscopic MRI

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
Whole‐brain spectroscopic MRI in recurrent glioblastoma revealed modest, dose‐dependent metabolic changes in previously irradiated normal‐appearing brain. N‐acetylaspartate declined with increasing prior radiation dose, while choline changed minimally, producing a baseline rise in Cho:NAA. These findings support patient‐specific dose‐correction maps to
Abram Abdou, Sulaiman Sheriff, Kelly Rojas, Miah Nicholls, Eric A. Mellon   +4 more
wiley   +1 more source

Has Glioblastoma Five- and Ten-Year Survival Been Affected by New Treatment Algorithms in Population-Based Data? A Retrospective Swedish Survey Between 1958 and 2015. [PDF]

Cancers (Basel)
Milos P, Ehinger E, Visse E, Siesjö P.
europepmc   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, Volume 37, Issue 4, Page 507-535, June 2026.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

Glioblastoma and PARP inhibitors: the importance of patient selection to maximize therapeutic benefits. A critical review. [PDF]

Front Oncol
Dima G, Di Nunno V, Aprile M, Gatto L, Tosoni A, Argento CM, Margotti M, Bartolini S, Franceschi E.   +8 more
europepmc   +1 more source

Epigallocatechin‐3‐Gallate Suppresses Glioma by Targeting Integrin αvβ3/FAK/ERK Signaling Axis and Matrix Metalloproteinases

Phytotherapy Research, Volume 40, Issue 6, Page 3079-3093, June 2026.
EGCG suppresses glioma progression by targeting integrin αvβ3/FAK/ERK signaling and inhibiting MMP‐2/MMP‐9‐mediated ECM degradation, thereby blocking proliferation, migration, invasion, and promoting apoptosis. ABSTRACT Epigallocatechin‐3‐gallate (EGCG), the most abundant and biologically active catechin in green tea, has been widely reported to ...
Rui Sun, Yonghan Pan, Ning Yang, Bing Kang, Hong Xiao, Xianglong Tang, Taiping Li, Mengjie Zhao   +7 more
wiley   +1 more source

Statement of Retraction: SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy. [PDF]

Bioengineered
europepmc   +1 more source

Management of Adult Patients With Isocitrate Dehydrogenase‐Mutant Gliomas in Australia: An Expert Position Statement From the Cooperative Trials Group for Neuro‐Oncology

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 392-403, June 2026.
Following maximal surgery when feasible, management of adult patients with isocitrate dehydrogenase (IDH)‐mutant glioma is complex and should be considered in a neuro‐oncology multidisciplinary context balancing disease control versus potential treatment‐associated toxicities. Options include continued surveillance, radiation therapy, chemotherapy, and/
Mark B. Pinkham, Hao‐Wen Sim, Rosalind L. Jeffree, Arian Lasocki, Dianne M. Legge, Frank Saran, Laveniya Satgunaseelan, Hui K. Gan   +7 more
wiley   +1 more source

Phase I/II Study of the CDK2/9 Inhibitor Fadraciclib in Combination with Chemotherapy in Children with Advanced Malignancies: Arm K of the AcSé-ESMART Trial. [PDF]

Target Oncol
Rubio-San-Simón A, Marshall LV, Karamouza E, André N, Abbou S, Rubino J, Nebchi S, Aerts I, Thebaud E, Brisset C, Ducassou S, Le Teuff G, Geoerger B.   +12 more
europepmc   +1 more source

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

British Journal of Pharmacology, Volume 183, Issue 11, Page 2947-2968, June 2026.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng, Meng Zhang, Libo Zhu, Wenqiang Qian, Jingjing Yan, Huidi Jiang, Yu Xin, Ying Zhang, Dongli Sun, Weidong Fei, Mengdan Zhao   +10 more
wiley   +1 more source

Isocitrate Dehydrogenase-Mutant Astrocytomas: Risk Stratification and Therapeutic Advance. [PDF]

MedComm (2020)
Wei S, Xu X, Bao J, Pan Z.
europepmc   +1 more source