Results 101 to 110 of about 3,993,230 (248)

The Influence of Daily Temperature Fluctuation on the Efficacy of Bioinsecticides on Spotted Wing Drosophila Larvae. [PDF]

Insects, 2022
Mastore M, Quadroni S, Rezzonico A, Brivio MF.   +3 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Factors affecting the quality of frozen large yellow croaker (Pseudosciaena crocea) in cold chain logistics: Retention time and temperature fluctuation. [PDF]

Food Chem X, 2023
Chu Y, Ding Z, Wang J, Xie J, Ding Y.
europepmc   +1 more source

Effect of temperature fluctuation on colour change and softening of postharvest sweet cherry. [PDF]

RSC Adv, 2021
Xin Y, Liu Z, Zhang Y, Shi X, Chen F, Liu K.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Effect of temperature fluctuation on hydrate-based CO2 separation from fuel gas

, 2011
A new method of temperature fluctuation is proposed to promote the process of hydrate-based CO2 separation from fuel gas in this work according to the dual nature of CO2 solubility in hydrate forming and non-hydrate forming regions [1].
Xu, Chungang, Chungang Xu, Cai, Jing, Chen, Zhaoyang, Li, Xiaosen, Xiaosen Li, Jing Cai, Zhaoyang Chen, Wu, Huijie, Huijie Wu   +9 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effect of temperature fluctuation on hydrate-based CO_2 separation from fuel gas

, 2011
A new method of temperature fluctuation is proposed to promote the process of hydrate-based CO_2 separation from fuel gas in this work according to the dual nature of CO_2 solubility in hydrate forming and non-hydrate forming regions 1.
Cai Jing, Chen Zhaoyang, Li Xiaosen, Xu Chungang, Wu Huijie   +4 more
core   +2 more sources

Effects of temperature fluctuations on the quality and characteristic volatile compounds of large yellow croaker (Pseudosciaena crocea) during cold chain logistics

Food Science of Animal Products
Large yellow croaker (Larimichthys crocea) is one of economic important mariculture fish species with abundant nutritional value, and usually stored at refrigerated temperature.
Jian Chen, Huangwei Ye, Huan Li, Yanbo Wang   +3 more
doaj   +1 more source