Results 211 to 220 of about 227,412 (325)

Nonenzymatic RNA copying with a potentially primordial genetic alphabet. [PDF]

Proc Natl Acad Sci U S A
Fang Z, Jia X, Xing Y, Szostak JW.
europepmc   +1 more source

Mechanisms of Anode Interfacial Phenomena and Multi‐perspective Optimization in Aqueous Alkaline Zinc‐Air Batteries

Advanced Functional Materials, EarlyView.
Zinc‐air batteries demonstrate great potential for sustainable energy storage but face major anode‐related challenges. This review provides a mechanism‐driven overview of zinc anode interfacial issues, e.g. dendrite formation, passivation, self‐corrosion, and hydrogen evolution; and explores advances in electrode, surface, and electrolyte engineering ...
Hong Zhao, Lianzhou Wang, Matthew Dargusch   +2 more
wiley   +1 more source

Chirality-Promoted Chemical Ligation and Reverse Transcription of <i>Acyclic</i> Threoninol Nucleic Acid. [PDF]

J Am Chem Soc
Okita H, Murayama K, Asanuma H.
europepmc   +1 more source

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel, Henning De May, Lauren Anderson, Lorél Y. Medina, Ellie Kennedy, Erica Flores, John O'Rourke, Marian Olewine, Irina Lagutina, Lillian Fitzpatrick, Fred Shultz, Donna F. Kusewitt, Eric Bartee, Sarah Adams, Achraf Noureddine, Rita E. Serda   +15 more
wiley   +1 more source

Assessment and Mitigation of CRISPR-Cas9-Induced Nontargeted Translocations. [PDF]

Adv Sci (Weinh)
Hou Z, Yi Q, Wu M, Wu L, Li F, Wang T, Bian P.   +6 more
europepmc   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

The 4977 Bp Deletion of Mitochondrial DNA as a Potential Trait Marker for Major Depressive Disorder. [PDF]

Neuropsychiatr Dis Treat
He Y, Yang X, Li Z, Liu W, Tang J, Chen X.   +5 more
europepmc   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source

Reinforcement learning for mutation operator selection in automated program repair. [PDF]

Autom Softw Eng
Hanna C, Blot A, Petke J.
europepmc   +1 more source

Hollow‐Structured Nanorobot with Excellent Magnetic Propulsion for Catalytic Pollutant Degradation, Anti‐Bacterial and Biofilm Removal

Advanced Healthcare Materials, EarlyView.
A hollow‐structured Fe3O4@AgAu@PDA‐ZnPc nanosphere has been developed, exhibiting controllable catalytic activity and “photothermal‐photodynamic‐Ag+” coupling antibacterial characteristics. When subjected to a rotating magnetic field, these performances are uniquely enhanced by magnetic propulsion, allowing the nanosphere to function as a magnetic ...
Jing Wang, Guangjin Yu, Qunling Fang, Yunqi Xu, Jie Zhang, Ailing Hui, Shouhu Xuan, Ken Cham‐Fai Leung   +7 more
wiley   +1 more source