Results 51 to 60 of about 3,144,500 (368)

Avoiding chromosome pathology when replication forks collide [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Macmillan Publishers Limited.Chromosome duplication normally initiates through the assembly of replication fork complexes at defined ...
Lloyd, RG, Nieduszynski, CA, Stockum, A, Upton, AL   +3 more
core   +1 more source

GASS-WEB: a web server for identifying enzyme active sites based on genetic algorithms

Nucleic Acids Res., 2017
Enzyme active sites are important and conserved functional regions of proteins whose identification can be an invaluable step toward protein function prediction.
João P. A. Moraes, G. Pappa, Douglas E. V. Pires, S. Izidoro   +3 more
semanticscholar   +1 more source

Genetic Algorithms for Searching a Matrix of Metagrammars for Synthesis [PDF]

arXiv, 2023
Syntax-guided synthesis is a paradigm in program synthesis in which the search space of candidate solutions is constrained by a syntactic template in the form of a grammar. These syntactic constraints serve two purposes: constraining the language to the space the user desires, but also rendering the search space tractable for the synthesizer.
arxiv  

Multi-site genetic analysis of diffusion images and voxelwise heritability analysis : a pilot project of the ENIGMA–DTI working group [PDF]

, 2013
The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium was set up to analyze brain measures and genotypes from multiple sites across the world to improve the power to detect genetic variants that influence the brain.
Almasy, Amos, Andersson, Andrew M. McIntosh, Arthur W. Toga, Barnes, Barysheva, Basser, Basser, Bennett A. Landman, Bezdjian, Bis, Blangero, Blokland, Boos, Braskie, Braskie, Braskie, Braxton D. Mitchell, Brouwer, Carballedo, Charles P. Peterson, Chen, Chiang, Chiang, Chiang, Chiang, Clark, Clerx, David C. Glahn, de Zubicaray, Deary, Deary, Dinov, Emma Sprooten, Gatt, Genovese, Glahn, Glahn, Greig I. de Zubicaray, Hasler, Hilleke E. Hulshoff Pol, Honea, Ian J. Deary, Ikram, Jahanshad, Jahanshad, Jahanshad, Jahanshad, Jenkinson, Jessika E. Sussmann, Joanna M. Wardlaw, Joanne E. Curran, John Blangero, John M. Starr, Karlsgodt, Katie L. McMahon, Kochunov, Kochunov, Kochunov, Kochunov, Kochunov, Kochunov, Kohannim, L. Elliot Hong, Laura Almasy, Li, Lopez, Mahmood, Malouff, Mandl, Mandl, Margaret J. Wright, Mark E. Bastin, McIntosh, Mori, Neda Jahanshad, Nicholas G. Martin, Nichols, Olvera, Paul M. Thompson, Penke, Penke, Peter T. Fox, Peter V. Kochunov, Rachel M. Brouwer, Ravi Duggirala, Rene L. Olvera, René C. Mandl, Sarah E. Medland, Smith, Sprooten, Sprooten, Sprooten, Stein, Sullivan, Sutton, Taal, Teipel, Teipel, Thomas E. Nichols, Thomason, Thompson, van den Heuvel, Verweij, Walker, Wardlaw, Weiner, Westlye, Winkler, Zhan, Zhu, Zuk, Zuliani   +113 more
core   +4 more sources

A methodology for procedural piano music composition with mood templates using genetic algorithms [PDF]

IET Conference Proceedings, 2021
Creating music in an automatic way has been studied since the beginning of artificial intelligence. One of the biggest obstacles of music generation is the vagueness and subjectivity of the mood or emotion transmitted by a music piece. In this work, we experiment with the generation of piano music using template pieces, represented in MIDI format, as a
Rocha de Azevedo Santos, Luisa, Silla Jr., Carlos, Da Costa Abreu, Marjory   +2 more
openaire   +2 more sources

Universal Multiplex PCR: a novel method of simultaneous amplification of multiple DNA fragments

Plant Methods, 2012
Background Multiplex PCR has been successfully applied in many areas since it was first reported in 1988; however, it suffers from poor universality.
Wen Daxing, Zhang Chunqing
doaj   +1 more source

Drug Resistance in Cancers: A Free Pass for Bullying

Cells, 2022
The cancer burden continues to grow globally, and drug resistance remains a substantial challenge in cancer therapy. It is well established that cancerous cells with clonal dysplasia generate the same carcinogenic lesions.
Jing Li, Xiao Li, Qie Guo
doaj   +1 more source

Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair. [PDF]

, 2020
Repair of double strand DNA breaks (DSBs) can result in gene disruption or gene modification via homology directed repair (HDR) from donor DNA. Altering cellular responses to DSBs may rebalance editing outcomes towards HDR and away from other repair ...
A Ferreira, A Montagnoli, A Orthwein, AC Komor, B Roberts, B Verdoodt, C Anders, C Yu, CD Richardson, CD Richardson, D Szklarczyk, DW Huang, E Lingeman, ES Koltun, FK Zimmermann, H Ghezraoui, J Song, JA Doudna, JE Haber, JP Duxin, K Jayathilaka, K Nakanishi, K Okita, KJ Livak, L Lei, L Pessoa-Brandão, LA Gilbert, LN Brandão, M Cavazzana, M Lei, M Yamada, MA DeWitt, MD Canny, MD Rainey, MH Porteus, N Hustedt, N Zielke, NK Sasi, NR Pannunzio, R Ceccaldi, RC Alver, S Hughes, S Lin, SB Thyme, T Maruyama, T Takenaka, T Tsuji, TA Day, TL Roth, TS Nambiar, U Eichenlaub-Ritter, VT Chu, W Li, X Liang, Z Romero   +54 more
core   +1 more source

Transcription of 4'-thioDNA templates to natural RNA in vitro and in mammalian cells.

Chemical Communications, 2015
Synthetic chemically modified nucleic acids, which are compatible with DNA/RNA polymerases, have great potential as a genetic material for synthetic biological studies.
Hideto Maruyama, K. Furukawa, H. Kamiya, N. Minakawa, A. Matsuda   +4 more
semanticscholar   +1 more source

GASS: identifying enzyme active sites with genetic algorithms

Bioinform., 2015
MOTIVATION Currently, 25% of proteins annotated in Pfam have their function unknown. One way of predicting proteins function is by looking at their active site, which has two main parts: the catalytic site and the substrate binding site.
S. Izidoro, R. Minardi, G. Pappa
semanticscholar   +1 more source