Results 61 to 70 of about 128,898 (315)

Ictal and Interictal Electroencephalography of Mesial and Lateral Temporal Lobe Epilepsy; A Comparative Study

Caspian Journal of Neurological Sciences, 2017
Background: Epilepsy is considered as one of the most important disorders in neurology. Temporal lobe epilepsy is a form of epilepsy including two main types of mesial and lateral (neocortex).
Jafar Mehvari, Mohammad Zare, Rooholla Andami, Keyvan Ghadimi, Nasim Tabrizi   +4 more
doaj  

Olfactory function in focal epilepsies: Understanding mesial temporal lobe epilepsy beyond the hippocampus

Epilepsia Open, 2019
Several lines of research have linked olfactory regions with the pathophysiology of focal epilepsies. Among those regions, the piriform cortex represents the major part of the primary olfactory cortex.
Camilo Espinosa‐Jovel, Rafael Toledano, Adolfo Jiménez‐Huete, Ángel Aledo‐Serrano, Irene García‐Morales, Pablo Campo, Antonio Gil‐Nagel   +6 more
doaj   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Temporal Lobe Malformations and Epilepsy

Pediatric Neurology Briefs, 1998
Temporal lobe developmental malformations (TLDM) (focal cortical dysplasia and balloon cells) occurred with mesial temporal sclerosis as dual pathologies in 87% of 30 patients with unilateral TLDM and intractable partial epilepsy treated at the UAB ...
J Gordon Millichap
doaj   +1 more source

Preoperative automated fibre quantification predicts postoperative seizure outcome in temporal lobe epilepsy

Brain : a journal of neurology, 2016
Approximately one in every two patients with pharmacoresistant temporal lobe epilepsy will not be rendered completely seizure-free after temporal lobe surgery. The reasons for this are unknown and are likely to be multifactorial.
Simon S. Keller, Simon S. Keller, Simon S. Keller, G. Glenn, B. Weber, Barbara A. K. Kreilkamp, Barbara A. K. Kreilkamp, J. Jensen, J. Helpern, Jan Wagner, Jan Wagner, G. Barker, Mark P. Richardson, Mark P. Richardson, L. Bonilha   +14 more
semanticscholar   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Clinical–Radiological Spectrum of Cerebral Amyloid Angiopathy‐Related Inflammation

Annals of Neurology, EarlyView.
Objective To identify clinical and radiological features of cerebral amyloid angiopathy‐related inflammation (CAA‐ri), and compare these features with those of sporadic CAA, to improve the understanding, diagnosis, and clinical care of CAA‐ri. Methods We retrospectively reviewed routine clinical data from 37 patients with CAA‐ri and 158 patients with ...
Larysa Panteleienko, Gargi Banerjee, Dermot Mallon, Kitti Thiankhaw, Rupert Oliver, Victoria Harvey, Gareth Ambler, Michael Zandi, Hans Rolf Jäger, David J. Werring   +9 more
wiley   +1 more source

Surgically treated intracranial supratentorial calcifying pseudoneoplasms of the neuraxis (CAPNON) with drug-resistant left temporal lobe epilepsy: A case report and review of the literature

Epilepsy and Behavior Case Reports, 2019
Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare pathological lesions that can present anywhere in the central nervous system. Symptoms vary depending on the location, though they often include seizures, especially in intracranial and ...
Yuta Tanoue, Takehiro Uda, Kosuke Nakajo, Shugo Nishijima, Tsuyoshi Sasaki, Kenji Ohata   +5 more
doaj   +1 more source

Episodic Memory Dysfunction and Effective Connectivity in Adult Patients With Newly Diagnosed Nonlesional Temporal Lobe Epilepsy [PDF]

, 2022
Aftab Bakhtiari, Agnes Balint Bjørke, Pål G. Larsson, Ketil Berg Olsen, Marianne Cecilie Johansen Nævra, Erik Taubøll, Kjell Heuser, Ylva Østby   +7 more
openalex   +1 more source

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Have Distinct Prediagnostic Blood Biochemical Profiles

Annals of Neurology, EarlyView.
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios, Jiali Gao, Carol A.C. Coupland, Julia Hippisley Cox, Martin R. Turner, Alexander G. Thompson   +5 more
wiley   +1 more source