Results 41 to 50 of about 19,761,197 (221)

Latent TGF-β Activation Is a Hallmark of the Tenascin Family

open access: yesFrontiers in Immunology, 2021
Transforming growth factor-β (TGF-β) isoforms are secreted as inactive complexes formed through non-covalent interactions between bioactive TGF-β entities and their N-terminal pro-domains called latency-associated peptides (LAP). Extracellular activation
Alexandre Aubert   +11 more
doaj   +1 more source

The role of tenascin C in cardiovascular disease [PDF]

open access: yesCardiovascular Research, 2011
The extracellular matrix protein tenascin C (TnC) is expressed in a variety of embryonic tissues, but its expression in adult arteries is co-incident with sites of vascular disease. TnC expression has been linked to the development and complications of intimal hyperplasia, pulmonary artery hypertension, atherosclerosis, myocardial infarction, and heart
Golledge, J.   +4 more
openaire   +3 more sources

A model for prognosis of development of left ventricular systolic dysfunction in patients with acute myocardial infarction and type 2 diabetes mellitus taking into account tenascin C level

open access: yesZaporožskij Medicinskij Žurnal, 2016
The aim of the study was to elaborate a model for prediction of development of left ventricular systolic dysfunction in patients with acute myocardial infarction (AMI) and type 2 diabetes mellitus taking into account tenascin C level and estimation of ...
M. Yu. Koteliukh
doaj   +1 more source

Pleiotropic Role of Tenascin-C in Central Nervous System Diseases: From Basic to Clinical Applications

open access: yesFrontiers in Neurology, 2020
The extracellular matrix is composed of a variety of macromolecular substances secreted by cells, which form a complex network that supports and connects tissue structures, regulates the morphogenesis of tissues, and maintains the physiological ...
Chen Hanmin   +5 more
doaj   +1 more source

Generation of a tenascin-C-CreER2 knockin mouse line for conditional DNA recombination in renal medullary interstitial cells. [PDF]

open access: yesPLoS ONE, 2013
Renal medullary interstitial cells (RMIC) are specialized fibroblast-like cells that exert important functions in maintaining body fluid homeostasis and systemic blood pressure.
Wenjuan He   +8 more
doaj   +1 more source

Revisiting the Tenascins: Exploitable as Cancer Targets?

open access: yesFrontiers in Oncology, 2022
For their full manifestation, tumors require support from the surrounding tumor microenvironment (TME), which includes a specific extracellular matrix (ECM), vasculature, and a variety of non-malignant host cells.
Richard P. Tucker, Martin Degen
doaj   +1 more source

Immunosuppression via Tenascin-C

open access: yesOncoscience, 2015
Metastasis accounts for most of the prostate cancer-related deaths, and the presence of more than two metastatic lymph nodes at radical prostatectomy and extended pelvic lymph node (PLN) dissection is an independent predictor of prostate cancer specific mortality [1], thus suggesting that PLN invasion is an important event in the history of the disease.
Matteo, Bellone   +2 more
openaire   +2 more sources

Transcriptional regulation of tenascin genes [PDF]

open access: yes, 2015
Extracellular matrix proteins of the tenascin family resemble each other in their domain structure, and also share functions in modulating cell adhesion and cellular responses to growth factors.
Chiquet-Ehrismann, Ruth   +5 more
core   +2 more sources

Localization of integrin heterodimer α9β1 on the surface of uterine endometrial stromal and epithelial cells in mice

open access: yesAnimal Cells and Systems, 2020
Previously, we reported that endometrial stromal (ES) and endometrial epithelial (EE) cells did not attach to tenascin C, indicating the absence of active integrin α9β1 on the surface of mouse ES and EE cells.
Hye Jin Park, Jung Im Yun, Seung Tae Lee
doaj   +1 more source

Associations Between Tenascin-C and Testosterone Deficiency in Men with Major Depressive Disorder: A Cross-Sectional Retrospective Study

open access: yesJournal of Inflammation Research, 2021
Rui Peng, Yan Li Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People’s Republic of ChinaCorrespondence: Yan LiDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, 238 ...
Peng R, Li Y
doaj  

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