Results 31 to 40 of about 19,761,197 (221)
Clinical significance and prognosis of serum tenascin-C in patients with sepsis
BMC Anesthesiology, 2018 Background Tenascin-C is a pro-inflammatory glycoprotein with various biological functions. High expression of tenascin-C is found in inflammation, tissue remodeling, and autoimmune diseases.
Weifang Yuan +5 more
doaj +1 more source
Tenascin-C fragments are endogenous inducers of cartilage matrix degradation [PDF]
, 2011 Cartilage destruction is a hallmark of osteoarthritis (OA) and is characterized by increased protease activity resulting in the degradation of critical extracellular matrix (ECM) proteins essential for maintaining cartilage integrity.
Hermansson, M +12 more
core +1 more source
Phylogenetic analysis of the tenascin gene family: evidence of origin early in the chordate lineage
BMC Evolutionary Biology, 2006 Background Tenascins are a family of glycoproteins found primarily in the extracellular matrix of embryos where they help to regulate cell proliferation, adhesion and migration.
Tucker RP +5 more
doaj +1 more source
Pediatric Rheumatology Online Journal, 2021 Background Tenascin-C (TN-C) is an extracellular matrix glycoprotein related to tissue inflammation. Our previous retrospective study conducted in 2016 revealed that the serum tenascin-C level was higher in patients with Kawasaki disease (KD) who were ...
Yukako Yoshikane +10 more
doaj +1 more source
Localization of tenascin in human skin wounds [PDF]
, 1993 A total of 56 surgically treated human skin wounds with a wound age between 8h and 7 months were investigated. Tenascin was visualized by immunohistochemistry and appeared first in the wound area pericellularly around fibroblastic cells approximately 2 ...
Penning, R. +4 more
core +1 more source
Tenascins : prominent molecules in tumor stroma [PDF]
, 2007 A very special connective tissue surrounds and interweaves solid tumors, the tumor stroma. Initially thought to only have a passive role, there is now more and more evidence accumulating that the tumor stroma plays an active function in the process of ...
Degen, Martin
core +1 more source
Clinical and Translational Allergy, 2021 Background Tissue remodeling caused by increased MMPs is involved in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). We previously found higher levels of periostin and tenascin C in CRSwNPs, but whether they are associated with ...
Kun Du +8 more
doaj +1 more source
Tenascin-C Signaling in melanoma
Cell Adhesion & Migration, 2014 Tenascin-C (TNC), a multifunctional matricellular glyco-protein, is highly expressed in the majority of melanoma cell lines and has been implicated in the progression of melanoma. A growing body of evidence has implicated the role of TNC in the process of invasion and metastasis for melanoma.
Hanshuang, Shao +2 more
openaire +2 more sources
Advances on the roles of tenascin-C in cancer
Journal of Cell Science, 2022 ABSTRACT The roles of the extracellular matrix molecule tenascin-C (TNC) in health and disease have been extensively reviewed since its discovery over 40 years ago. Here, we will describe recent insights into the roles of TNC in tumorigenesis, angiogenesis, immunity and metastasis.
Alev Yilmaz +9 more
openaire +3 more sources
, 2022 Sepsis is a life-threatening condition, characterized by organ dysfunction and a dysregulated host response to infection. Despite having been a major cause of intensive care unit (ICU) mortality for decades, our understanding of its pathophysiology is still limited.
openaire +3 more sources