Results 11 to 20 of about 19,761,197 (221)
ABSTRACT Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin.
Midwood, Kim +3 more
core +8 more sources
The Adhesion Modulating Properties of Tenascin-W [PDF]
Tenascins are extracellular matrix glycoproteins associated with cell motility, proliferation and differentiation. Tenascin-C inhibits cell spreading by binding to fibronectin; tenascin-R and tenascin-X also have anti-adhesive properties in vitro.
Florence Brellier, Enrico Martina, Matthias Chiquet, Jacqueline Ferralli, Michael van der Heyden, Gertraud Orend, Johannes C. Schittny, Ruth Chiquet-Ehrismann, Richard P. Tucker
doaj +3 more sources
Tenascin-C Suppresses Rho Activation [PDF]
Cell binding to extracellular matrix (ECM) components changes cytoskeletal organization by the activation of Rho family GTPases. Tenascin-C, a developmentally regulated matrix protein, modulates cellular responses to other matrix proteins, such as fibronectin (FN).
Wenk, M, Midwood, K, Schwarzbauer, J
openaire +4 more sources
Attenuated expression of tenascin-c in ovalbumin-challenged STAT4-/- mice [PDF]
Background Asthma leads to structural changes in the airways, including the modification of extracellular matrix proteins such as tenascin-C. The role of tenascin-C is unclear, but it might act as an early initiator of airway wall remodelling, as its ...
Virtanen Ismo +11 more
doaj +3 more sources
TNC (tenascin C (hexabrachion)) [PDF]
Review on TNC (tenascin C (hexabrachion)), with data on DNA, on the protein encoded, and where the gene is implicated.
M Degen, R Chiquet-Ehrismann
openaire +2 more sources
Tenascin-C as a cardiovascular marker
Novel biological markers, such as fibrosis marker galectin-3, peptide hormone adrenomedullin, soluble ST2, chemokine CX3CL1, surrogate marker of vasopressin, and others, are every year one step closer to being introduced into health practice.
A. M. Alieva +9 more
doaj +2 more sources
Expression and Immune Function of Tenascin-C
Our immune system is designed to protect us from danger. Upon pathogen invasion and tissue injury, activation of both innate and adaptive immunity enables us to combat infection and to repair tissue damage. Tenascin-C is a large, extracellular matrix glycoprotein that has a very tightly controlled pattern of expression.
Udalova, I +3 more
openaire +4 more sources
Serendipity; Close Encounter of Tenascin C [PDF]
In 1924, Hans Spemann and Hilde Mangold established the concept of embryonic induction (1). They transplanted the dorsal grey crescent region of one newt gastrula to the ventral part of another newt gastrula and found that a piece of the transplant induced the host tissue into the formation of a secondary embryo.
Teruyo Sakakura
doaj +3 more sources
Role of Serum Tenascin-C in Sepsis [PDF]
Background: Sepsis can range in severity from infection to septic shock, and it can result in multiple organ dysfunction syndrome (MODS) and death. Tenascins are extracellular matrix glycoproteins that are expressed during multicellular organism growth ...
nora said +3 more
doaj +3 more sources
TENASCIN-C EXPRESSION IN ENDOMETRIOSIS
Objective: To investigate the expression of Tenascin-C (TN-C) in endometrium and endometriosis.
Zekioglu, Osman +6 more
core +3 more sources

