Results 151 to 160 of about 303,650 (308)

Machine Learning to Predict Remission Between Six and 24 Months in Rheumatoid Arthritis: Insights from the JAK‐pot Collaboration

Arthritis &Rheumatology, Accepted Article.
Objective To develop, externally validate, and simplify a machine‐learning (ML) model to predict remission between six and 24 months in rheumatoid arthritis (RA) patients initiating TNF inhibitors, JAK inhibitors, IL‐6 inhibitors, abatacept, or rituximab, using data from 11 international registries in the JAK‐pot collaboration.
Zubeyir Salis, Denis Mongin, Denis Choquette, Louis Coupal, Catalin Codreanu, Florenzo Iannone, Roberto Caporali, Tore K Kvien, Sella Provan, Ruth Fritsch‐Stork, Dan Nordström, Nina Trokovic, Karel Pavelka, Jakub Závada, Ana Rodrigues, Ziga Rotar, Prodromos Sidiropoulos, Irini Flouri, Céline Lamacchia, Michele Iudici, Delphine Courvoisier, Kim Lauper, Axel Finckh   +22 more
wiley   +1 more source

Inferring rheumatoid arthritis disease activity status from the electronic health records across health systems

Arthritis &Rheumatology, Accepted Article.
Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHR) data has limited the ability to generate real‐world evidence (RWE). This study aimed to develop and validate scalable machine learning (ML) models to infer
David Cheng, Xuan Wang, Gregory C. McDermott, Jennifer S. Hanberg, Zoe Love, Katherine Zhong, Mary Jeffway, Jue Hou, Vidul Panickan, Rahul Sangar, Ying Qi, Connor Melley, Lauren Costa, Dakota Feil, Rachael Matty, Dana Weisenfeld, Abisayo Animashaun, Aimee Schreiner, Sara Morini, Lauren Rusnak, Andrew Cagan, Misti Paudel, J. Michael Gaziano, Brian Sauer, Michael Weinblatt, Joshua Baker, Bryant England, Yuk‐Lam Ho, Kelly Cho, Paul Monach, Grant W. Cannon, Nancy Shadick, Ted R. Mikuls, Tianxi Cai, Katherine P. Liao   +34 more
wiley   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis within a Longitudinal Cohort

Arthritis &Rheumatology, Accepted Article.
Objective To estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axSpA and to identify factors associated with D2M/TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis Program cohort.
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Endoscopic Resection of Bizarre Parosteal Osteochondromatous Proliferation of the Calcaneocuboid Joint

Arthroscopy Techniques, EarlyView.
Abstract Bizarre parosteal osteochondromatous proliferation (BPOP), or Nora's lesion, is an unusual, benign, parosteal lesion comprising bone, fibrous tissue, and cartilage. Clinically, the lesions present as slowly growing hard protuberances that are painless in most cases unless they cause local symptoms due to mass effect, including pain, palpable ...
Tun Hing Lui, Kit Leung
wiley   +1 more source

Endoscopic Adhesiolysis of Peroneal Tendons via Distal Portals

Arthroscopy Techniques, EarlyView.
Abstract Fibrous adhesions of the peroneal tendons can occur at the retromalleolar space and around the lateral malleolar tip with different peroneal pathology or after operations at this region, especially open surgery. This can cause tightness and pain at the posterolateral ankle. Surgery is indicated if symptoms persist after physiotherapy. Whenever
Tun Hing Lui, Yan Yui Benedict Cheung
wiley   +1 more source

Arthroscopic Anterior and Posterior Glenohumeral Capsular Augmentation With Gracilis Allograft

Arthroscopy Techniques, EarlyView.
Abstract Multidirectional instability in patients with connective tissue disorders such as Ehlers‐Danlos syndrome (EDS) is difficult to treat due to poor tissue quality and frequent failure of standard repairs. We describe an arthroscopic technique using gracilis tendon allografts to perform an anterior and posterior capsular augmentation in the ...
Michael D. Maloney, Omkar N. Prabhavalkar, Samantha Levin, Richard Lander, Brett P. Salazar, Sandeep Mannava   +5 more
wiley   +1 more source

Surgical Technique for Treating Focal Osteochondral Knee Lesions Using an Aragonite‐Based Biphasic Scaffold

Arthroscopy Techniques, EarlyView.
Abstract Osteochondral lesions of the knee, particularly in patients with early osteoarthritic changes, remain a clinical challenge. The Agili‐C implant (CartiHeal, Smith & Nephew), an aragonite‐based osteochondral scaffold, offers a single‐stage, off‐the‐shelf solution designed to regenerate both cartilage and subchondral bone.
Eric Wang, Alexandra M. Cancio‐Bello, Katelyn T. Koschmeder, Bryn Berens, Anikar Chhabra   +4 more
wiley   +1 more source

THE EFFECT OF LENGTH OF SOAKING IN PAPAIN ON MEAT WATER CONTENT, pH AND TENDERNESS OF CULLED LAYER HENS

Животновъдни науки, 2014
Twenty culled layer hens was test on the effect of length of soaking in papain on meat water content, pH and tenderness. The length of soaking are 15, 30, 45 and 60 minutes; and the experiment used Completely Randomized Design (CRD), and each treatment ...
HENDRONOTO ARNOLDUS W LENGKEY, DANI GARNIDA, LILIES SURYANINGSIH   +2 more
doaj  

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

The Strategic Role of Waste Inventories in Industrial Symbiosis: A Simulation‐Based Perspective on Performance and Resilience of Industrial Symbiosis Networks

Business Strategy and the Environment, EarlyView.
ABSTRACT Ensuring the resilience of industrial symbiosis networks (ISNs) has emerged as a key concern in the literature. However, existing studies focus on network‐level strategies, neglecting the potential benefits derived from strengthening the links between symbiotic partners.
Melissa Mollica, Alberto Nastasi, Luca Fraccascia   +2 more
wiley   +1 more source