Results 131 to 140 of about 303,650 (308)

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Polymorphism in the Calpastatin Gene Alters Beef Tenderization in Excitable Cattle: A Preliminary Study

Animals
The variability in beef tenderness is a problem for industry and can be difficult to overcome, especially for Bos taurus indicus cattle. The objective of this study was to determine the association between calpastatin (CAST) polymorphisms (Single ...
Ana Cláudia da Silva, Patricia Maloso Ramos, Aline Silva Mello César, João Pedro Sousa do Vale, Saulo da Luz e Silva, Eduardo Francisquine Delgado   +5 more
doaj   +1 more source

Hiding Behind the Closet Door: Representations of the Homosexual Experience in A Streetcar Named Desire [PDF]

, 2018
Themes related to homosexuality and the homosexual experience are interwoven in many layers throughout Tennessee Williams’ A Streetcar Named Desire. This research paper analyzes contemporary commentary on homosexuality from the 1940s and ‘50s, Blanche’s ...
Piccirillo, Antonia
core   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

Arthritis &Rheumatology, EarlyView.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, for the TULIP‐SC investigators   +12 more
wiley   +1 more source

The Early Methionine Supplementation of Ewe Lambs (F0) Modifies Meat Quality Traits of the Progeny (F1, Male Fattening Lambs)

Animals
Adequate management of replacement ewe lambs (F0) in dairy sheep farms during postnatal life may modify the germline cells, thus promoting transmission of intergenerational effects to the offspring (F1). To test this hypothesis, 18 newborn male lambs (F1)
Mahsa Dehnavi, Javier Mateo, Alba Martín, F. Javier Giráldez, Irma Caro, Lara Morán, Sonia Andrés   +6 more
doaj   +1 more source

Effect of slaughter age between 5 and 14 months on the quality of sheep meat with specific focus on collagen concentration and solubility : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Animal Science at Massey University, Manawatu, New Zealand [PDF]

, 2017
In New Zealand, pasture-raised lamb is considered the highest quality sheep meat product while hogget is a downgraded product considered to be of poorer quality.
Mashele, Grace Arbogast
core  

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

Arthritis &Rheumatology, EarlyView.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller, Steven E. Harte, Richard E. Harris, Andrew Schrepf, Tristin Smith, Eric Ichesco, Chelsea Kaplan, Flavia Sunzini, Deeba Minhas, Wendy Marder, Sara R. Till, David A. Williams, Chad M. Brummett, Neil Basu, Sawsan As‐Sanie, Daniel J. Clauw   +15 more
wiley   +1 more source

Influence of diverse finishing systems on carcass characteristics, proximate composition, and meat quality attributes of striploins from bison heifers

Frontiers in Ecology and Evolution
Bison producers commonly utilize grain- or grass-finishing across both extensive and intensive management systems that can vary in diet composition and nutrient concentration.
Lydia M. O’Sullivan, Reid F. Anema, Garrett T. Weldy, Benjamin J. Carpenter, M. Sebastian Hernandez, Keith R. Underwood, Judson K. Grubbs, Christina E. Bakker, Jerrad F. Legako, Jessica Lovitt, Carter Kruse, Amanda D. Blair   +11 more
doaj   +1 more source

Growth and sensory characteristics of alternative genotype broilers reared in organic orchards [PDF]

, 2005
The effects of age, sex and genotype on growth and sensory characteristics in organically produced broilers, when kept considerably longer before slaughtering, were examined. A total of 450 birds consisting of three genotypes, Light Sussex, New Hampshire,
Henning, Judith, Hermansen, John E., Horsted, Klaus   +2 more
core  

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source