Results 131 to 140 of about 1,312,393 (235)

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Early synovial regulatory T cell engagement in posttraumatic osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source

Injectable Zein-Based Photothermal Composite Hydrogel Enhances Osteoporotic Tendon-Bone Healing. [PDF]

Small Methods
Ye K, Ding P, Dong Z, Shi W, Shen L, Zheng X.   +5 more
europepmc   +1 more source

Shared and Distinguishing Features of Late‐Onset Rheumatic Diseases Fulfilling Polymyalgia Rheumatica Classification Criteria

Arthritis &Rheumatology, Accepted Article.
‐
Kerem Abacar, Ala Altaie, Andrew Barr, Sarah L. Mackie, Kulveer Mankia, Dennis McGonagle   +5 more
wiley   +1 more source

The dead still teach the living: Body donor dissection in the digital age of anatomy education

Anatomical Sciences Education, EarlyView.
Abstract Donor‐based dissection has become increasingly contested in modern medical curricula as digital anatomy platforms, simulation technologies, virtual dissection tables, three‐dimensional reconstructions, and artificial intelligence‐supported learning have expanded.
Uğur Baran Kasırga
wiley   +1 more source

Low-intensity stimulation drives macrophage efferocytosis via ACSL4 lipid remodeling and CCL9-CCR1 signaling for tendon-bone healing. [PDF]

Sci Adv
Yao J, Wu Y, Wang X, Zhang J, Shao Y, Chen H, Zhang H, Li H, Pan J, Zhao Y, Cai D, Xie D, Zeng C.   +12 more
europepmc   +1 more source

Guidelines for designing and implementing game‐based learning in comparative anatomy education

Anatomical Sciences Education, EarlyView.
Abstract Game‐based learning (GBL) is increasingly used in health professions anatomy education to promote engagement, knowledge acquisition, collaboration, and application of knowledge. However, its application to comparative veterinary anatomy remains fragmented, with limited guidance on how games can be systematically designed around the specific ...
Arthur Chin Haeng Lau, Renato Lopes Previdelli   +1 more
wiley   +1 more source

Photosensitive and extracellular matrix-mimicking hydrogels promote the tendon-bone healing in rotator cuff injury. [PDF]

J Mater Sci Mater Med
Liu Y, Mao H, Tian Z, Wang X, Bao C, An B, Yang C.   +6 more
europepmc   +1 more source

Weak link of tendon-bone healing and a control experiment to promote healing

, 2013
This study aims to observe the mechanical weak point and histological features of tendon-bone interface after anterior cruciate ligament reconstructive surgery and to explore the tendon-bone healing effects of the platelet-rich gel (PRG) + deproteinized ...
Gao, Yuechuan, Chen, Zhiwen, Zhai, Wenliang, 陈志文, 翟文亮, 丁真奇, Lv, Chenwei, Zheng, Yanmei, Ding, Zhenqi   +8 more
core