Abstract Multiple strategies for rotator cuff augmentation have been developed to promote tendon healing and decrease retear rates. Previously published techniques and clinical studies have primarily emphasized biologic adjuncts intended to alter the local healing environment at the repair site or structural reinforcement with grafts.
Matthew D. Smith +2 more
wiley +1 more source
Total Flavonoids of <i>Rhizoma drynariae</i> Enhance Bone Marrow Mesenchymal Stem Cell-Mediated Tendon-Bone Healing by Promoting Tissue Regeneration, Angiogenesis, and Modulation of Cytokine Expression. [PDF]
Yang G +9 more
europepmc +1 more source
Abstract Massive rotator cuff tears in osteoporotic bone often fail because of many factors, including poor anchor fixation. We present an arthroscopic hybrid double‐row repair technique using a unicortical cancellous screw and washer for lateral‐row fixation, combined with biceps superior capsular reconstruction.
Pakorn Chawanpaiboon +4 more
wiley +1 more source
Natural fish swim bladder-derived MPN-nanofibrous biomimetic system exhibit ECM-responsive signal regulation and promote robust tendon-bone healing. [PDF]
Shi L +7 more
europepmc +1 more source
Abstract Irreparable rotator cuff tears remain a challenging condition to manage surgically, particularly in young and active patients without significant glenohumeral osteoarthritis. Several solutions have been proposed, and more recently, superior capsular reconstruction using the long head of the biceps tendon has shown promising results using an ...
Julian Devigne +2 more
wiley +1 more source
Bone marrow mesenchymal stem cell-derived exosomal lactate dehydrogenase A promotes tendon-bone healing <i>via</i> histone lactylation-mediated cartilage regeneration. [PDF]
Zhang T, Huang Q, Gan KF.
europepmc +1 more source
Abstract Combined anterior cruciate ligament and anterolateral ligament reconstruction is indicated for patients with anterior cruciate ligament rupture and preoperative rotatory instability. In smaller patients, the smaller graft diameter and shorter lengths of the gracilis and semitendinosus graft may not be sufficient for performing a combined ...
Cheuk‐Wai Wong +4 more
wiley +1 more source
SHED-derived exosome-mimetics promotes rotator cuff tendon-bone healing via macrophage immunomodulation through NF-κB suppression and autophagy activation. [PDF]
He Y +11 more
europepmc +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
Letter to the Editor: Leptin Enhances M1 Macrophage Polarization and Impairs Tendon-Bone Healing in Rotator Cuff Repair: A Rat Model. [PDF]
Cai X, Wang B, Cheng L, Ou Q.
europepmc +1 more source

