Abstract Background Proximal interphalangeal joint osteoarthritis (PIPJ OA) is a common cause of poor performance in the equine athlete; however, the supporting soft tissue structures surrounding the joint are seldom evaluated. Straight sesamoidean ligament injuries have been previously hypothesised to be concomitant with PIPJ OA; however, the ...
Charlotte K. Barton +3 more
wiley +1 more source
Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing. [PDF]
Shen Y +7 more
europepmc +1 more source
Abstract Background Musculoskeletal injury is a major welfare and economic challenge in racehorses, with stress‐related bone injury contributing to training interruption and catastrophic failure. Advanced imaging modalities can detect early skeletal pathology but remain limited in routine screening environments.
Peter Tually +7 more
wiley +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
First report of the long‐term sonographic appearance after ultrasound‐guided fasciotomy for chronic exertional compartment syndrome. Six‐month ultrasound demonstrated persistent fascial separation associated with excellent clinical outcomes. ABSTRACT We report the case of a 38‐year‐old recreational female runner with anterior and lateral chronic ...
Alexandre Lavigne +2 more
wiley +1 more source
[Effect of autologous osteochondral tissue and periosteum transplantation on tendon-bone healing of rotator cuff in rabbits]. [PDF]
Fang S +7 more
europepmc +1 more source
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat +7 more
wiley +1 more source
3D-printed Mg-incorporated PCL-based scaffolds improves rotator cuff tendon-bone healing through regulating macrophage polarization. [PDF]
Wang T +6 more
europepmc +1 more source
Controlled-release hydrogel loaded with magnesium-based nanoflowers synergize immunomodulation and cartilage regeneration in tendon-bone healing. [PDF]
Li J +15 more
europepmc +1 more source
Diabetes mellitus impairs tendon-bone healing after rotator cuff repair [PDF]
Studies have demonstrated a significant decrease in skeletal mass, bone mineral density, and impaired fracture healing in the diabetic population. However, the effect of sustained hyperglycemia on tendon-to-bone healing is unknown.Forty-eight male, Lewis rats underwent unilateral detachment of the supraspinatus tendon followed by immediate anatomic ...
Asheesh Bedi +2 more
exaly +3 more sources

