Results 41 to 50 of about 458,172 (134)

Tendon mechanobiology in the context of tendon biofabrication

Frontiers in Bioengineering and Biotechnology
Tendons are often affected by injuries or tendinopathies, resulting in serious and long-lasting impairments. The repair capacity is very low with a high risk of rerupture.
Clemens Gögele, Girish Pattappa, Herbert Tempfer, Herbert Tempfer, Denitsa Docheva, Gundula Schulze-Tanzil   +5 more
doaj   +1 more source

Tissue‐engineered tendon nano‐constructs for repair of chronic rotator cuff tears in large animal models

Bioengineering & Translational Medicine, 2023
Chronic rotator cuff tears (RCTs) are one of the most common injuries of shoulder pain. Despite the recent advances in surgical techniques and improved clinical outcomes of arthroscopically repaired rotator cuffs (RCs), complete functional recovery ...
Yonghyun Gwon, Woochan Kim, Sunho Park, Yang‐Kyung Kim, Hyoseong Kim, Myung‐Sun Kim, Jangho Kim   +6 more
doaj   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science
Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration. Although tendon stem/progenitor cells (TSPCs) are pivotal for tendon engineering, achieving microstructure and functional ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
doaj   +1 more source

The Achilles tendon total rupture score : a study of responsiveness, internal consistency and convergent validity on patients with acute Achilles tendon ruptures [PDF]

, 2012
Background The Achilles tendon Total Rupture Score was developed by a research group in 2007 in response to the need for a patient reported outcome measure for this patient population.
Costa, Matthew L., Lamb, S. E. (Sallie E.), Parsons, Nicholas R., Kearney, Rebecca S., Achten, Juul, Achten, J, Lamb, Sarah, Costa, ML, Kearney Rebecca S, Achten Juul, Parsons, N, Lamb Sarah E, Parsons Nicholas, Costa Matthew L, Kearney, RS, Lamb, SE   +15 more
core   +1 more source

Energy‐Supporting Enzyme‐Mimic Nanoscaffold Facilitates Tendon Regeneration Based on a Mitochondrial Protection and Microenvironment Remodeling Strategy

Advanced Science, 2022
Tendon injury is a tricky and prevalent motor system disease, leading to compromised daily activity and disability. Insufficient regenerative capability and dysregulation of immune microenvironment are the leading causes of functional loss.
Shikun Wang, Zhixiao Yao, Xinyu Zhang, Juehong Li, Chen Huang, Yuanming Ouyang, Yun Qian, Cunyi Fan   +7 more
doaj   +1 more source

Endogenous tenocyte activation underlies the regenerative capacity of the adult zebrafish tendon

npj Regenerative Medicine, 2023
Tendons are essential, frequently injured connective tissues that transmit forces from muscle to bone. Their unique highly ordered, matrix-rich structure is critical for proper function. While adult mammalian tendons heal after acute injuries, endogenous
Stephanie L. Tsai, Steffany Villaseñor, Rishita R. Shah, Jenna L. Galloway   +3 more
doaj   +1 more source

Engineering an extracellular matrix-functionalized, load-bearing tendon substitute for effective repair of large-to-massive tendon defects

Bioactive Materials
A significant clinical challenge in large-to-massive rotator cuff tendon injuries is the need for sustaining high mechanical demands despite limited tissue regeneration, which often results in clinical repair failure with high retear rates and long-term ...
Shuting Huang, Ying Rao, Meng Zhou, Anna M. Blocki, Xiao Chen, Chunyi Wen, Dai Fei Elmer Ker, Rocky S. Tuan, Dan Michelle Wang   +8 more
doaj   +1 more source

Torque and workspace analysis for flexible tendon driven mechanisms [PDF]

, 2010
Tendon driven mechanisms have been considered in robotic design for several decades. They provide lightweight end effectors with high dynamics. Using remote actuators it is possible to free more space for mechanics or electronics.
Chalon, Maxime, Hirzinger, Gerd, Thomas Wimböck, Wimboeck, Thomas, Gerd Hirzinger, Maxime Chalon   +5 more
core   +1 more source

A Regenerated Achilles Tendon with Good Function One Year After Total Extirpation Due to Infection – A Case Report

International Medical Case Reports Journal, 2022
Martin Granath,1 Pär Hedlund,1 Christoph Spang,2 Håkan Alfredson3,4 1Orthopaedic Department, Hässleholm Hospital, Hässleholm, Sweden; 2Private Orthopaedic Spine Center, Würzburg, Germany; 3Institute of Sports Exercise and Health, University College ...
Granath M, Hedlund P, Spang C, Alfredson H   +3 more
doaj  

Chapter 9 The veterinarian perspective: Comparative anatomy, equine models and in vivo bioengineering of tendons

Tendinopathy is common in humans and it is generally accepted that the pathogenesis involves preceding age-related degenerative changes to the tendon associated with repetitive loading that predispose it to injury during exercise. Unfortunately there has
Rosa, Gustavo S. [UNESP], Alves, Ana Liz G. [UNESP], Dudhia, Jayesh, Smith, Roger K.W.   +3 more
core   +1 more source