Results 41 to 50 of about 21,653 (110)

Engineering a stem cell-embedded bilayer hydrogel with biomimetic collagen mineralization for tendon-bone interface healing

Bioactive Materials
The tendon-bone interface effectively transfers mechanical stress for movement, yet its regeneration presents significant clinical challenges due to its hierarchical structure and composition.
Tingyun Lei, Tao Zhang, Tianshun Fang, Jie Han, Chunyi Gu, Youguo Liao, Yang Fei, Junchao Luo, Huanhuan Liu, Yan Wu, Weiliang Shen, Xiao Chen, Zi Yin, Junjuan Wang   +13 more
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Editorial: Tendinopathy Research- How Cutting Edge Developments Inform the Future Therapeutic Landscape

Frontiers in Bioengineering and Biotechnology, 2022
Stephanie G. Dakin, Alayna E. Loiselle, Andreas Traweger   +2 more
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Platelet-derived exosomes alleviate tendon stem/progenitor cell senescence and ferroptosis by regulating AMPK/Nrf2/GPX4 signaling and improve tendon-bone junction regeneration in rats

Journal of Orthopaedic Surgery and Research
Background Tendon stem/progenitor cell (TSPC) senescence contributes to tendon degeneration and impaired tendon repair, resulting in age-related tendon disorders.
Deheng Chen, Qian Tang, Wei Song, Yaohua He   +3 more
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Understanding Tendon Fibroblast Biology and Heterogeneity

Biomedicines
Tendon regeneration has emerged as an area of interest due to the challenging healing process of avascular tendon tissue. During tendon healing after injury, the formation of a fibrous scar can limit tendon strength and lead to subsequent complications ...
Sarah E. DiIorio, Bill Young, Jennifer B. Parker, Michelle F. Griffin, Michael T. Longaker   +4 more
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Grafts in tendon repair

Materials Today Bio
Inferior healing after tendon rupture often necessitates the use of grafts to reinforce tendon repair and promote the regeneration of functional tissue.
Miao Zhang, Suzanne M. Mithieux, Ziyu Wang, Anthony S. Weiss   +3 more
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Human tendon stem/progenitor cell-derived extracellular vesicle production promoted by dynamic culture

Artificial Cells, Nanomedicine, and Biotechnology
Tendon injuries significantly impact quality of life, prompting the exploration of innovative solutions beyond conventional surgery. Extracellular Vesicles (EVs) have emerged as a promising strategy to enhance tendon regeneration.
Marta Clerici, Maria Camilla Ciardulli, Erwin Pavel Lamparelli, Joseph Lovecchio, Emanuele Giordano, Tina P. Dale, Nicholas R. Forsyth, Nicola Maffulli, Giovanna Della Porta   +8 more
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Recent advances in immunoregulatory biomaterials for tendon healing: From immune remodeling to functional regeneration

Materials Today Bio
Tendon injury is a prevalent musculoskeletal disorder characterized by delayed healing, functional impairment, and diminished quality of life. Tendon repair is a dynamic process driven by immune regulation of tissue remodeling.This review summarizes the ...
Jinbo Zhang, Qing Han, Xue Zhao, Xingzhen Li, Aobo Zhang, Yang Liu, Jincheng Wang, Hao Chen   +7 more
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Regeneration process of severed rabbit common calcanean tendons influenced by external compression

Journal of Orthopaedic Surgery and Research
Background Limited research has focused on the correlation between an external compression and the regeneration of ruptured Achilles tendons. The aim of this study was to evaluate the influence of a constricted paratenon with external compression on the ...
Helin Wu, Xiaojing Dai, Lixia Huang, Xiaoyu Li, Shijun Wei, Feng Xu   +5 more
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Advanced bioactive materials and strategies for tendon repair and function restoration

Journal of Orthopaedic Translation
Tendon injury is one of the most common clinical challenges in musculoskeletal disorders. Effective tendon repair is crucial for restoring patients' motor function and improving their quality of life. Recent advances in bioactive material-mediated tendon
Sidan Wang, Zixuan Ou, Feng Xiao, Xiaobo Feng, Lei Tan, Shuangshuang Cheng, Di Wu, Cao Yang, Haoqun Yao   +8 more
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Stem cell technology for tendon regeneration: current status, challenges, and future research directions

Stem Cells and Cloning: Advances and Applications, 2015
Pauline Po Yee Lui Headquarter, Hospital Authority, Hong Kong SAR, People's Republic of China Abstract: Tendon injuries are a common cause of physical disability.
Lui PP
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