Comparative effectiveness and safety of tenecteplase versus alteplase for intravenous thrombolysis in acute ischemic stroke: a retrospective study [PDF]
BackgroundTenecteplase has been proposed as a practical alternative to alteplase for intravenous thrombolysis in acute ischemic stroke. Although randomised trials have demonstrated noninferiority, data from real-world comparative cohorts remain limited ...
Weili Zhao +4 more
doaj +2 more sources
Tenecteplase versus alteplase for acute ischemic stroke. [PDF]
Prabhakar H +4 more
europepmc +3 more sources
Tenecteplase for Ischemic Stroke due to Large Vessel Occlusion at 4.5 to 24 Hours: A Meta-Analysis of Randomized Controlled Trials. [PDF]
Question: Is it safe and effective to use tenecteplase for acute ischemic stroke patients beyond 4.5 h? Finding: This meta‐analysis of randomized controlled trials manifested that tenecteplase administered within 4.5 to 24 h for large vessel occlusion stroke was superior to control for an excellent functional outcome without safety concerns.
Wu S +10 more
europepmc +2 more sources
European Stroke Organisation (ESO) expedited recommendation on tenecteplase for acute ischaemic stroke [PDF]
Sonia Alamowitch +2 more
exaly +2 more sources
Abstract 082: Outcomes of Tenecteplase vs Alteplase in Acute Telestroke Care
Hall N +5 more
europepmc +2 more sources
Prospective Observational Cohort Study of Tenecteplase Versus Alteplase in Routine Clinical Practice [PDF]
Steven J Warach +2 more
exaly +2 more sources
Background The optimal dose of tenecteplase in acute ischemic stroke remains to be defined. We present a pooled analysis of the 2 NOR‐TESTs (Norwegian Tenecteplase Stroke Trials) exploring the efficacy and safety of tenecteplase, 0.4 mg/kg.
Vojtech Novotny +6 more
doaj +1 more source
Simultaneous Intracranial and Spinal Hemorrhage Following Tenecteplase Thrombolysis for ST‐Elevation Myocardial Infarction: A Case Report [PDF]
ABSTRACT Central nervous system (CNS) hemorrhage is a serious complication of intravenous thrombolysis. Tenecteplase, a fibrin‐specific thrombolytic agent, has a lower risk of hemorrhage than other agents. We report the first documented case of simultaneous intracranial and spinal hemorrhage following intravenous administration of tenecteplase.
Palliyaguru T +4 more
europepmc +2 more sources
Introduction Tenecteplase is increasingly being used as a first‐line treatment for acute ischemic stroke after several randomized studies demonstrated its safety and efficacy, resulting in a massive increase in the number of published studies on this ...
Brendan Huang
doaj +1 more source

