Results 21 to 30 of about 5,941 (179)

Sex Differences in Outcomes After Tenecteplase for Minor Stroke: A Subanalysis of the TEMPO‐2 Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In this subanalysis of the TEMPO‐2 (Tenecteplase Versus Standard of Care for Minor Ischaemic Stroke With Proven Occlusion) trial, a randomized clinical trial comparing tenecteplase and nonthrombolytic control in patients with minor stroke and ...
Amy Y. X. Yu, Shabnam Vatanpour, Aravind Ganesh, Thalia S. Field, Philip A. Barber, Philip M. C. Choi, Brian Buck, Timothy Kleinig, Carlos A. Molina, Bruce C. V. Campbell, Ramana Appireddy, Keith W. Muir, Michael D. Hill, Shelagh B. Coutts   +13 more
doaj   +1 more source

Tenecteplase in Pulmonary Embolism Patients: A Meta-Analysis and Systematic Review

Frontiers in Medicine, 2022
ObjectiveTo assess the efficacy and safety of tenecteplase in patients with pulmonary embolism (PE).MethodsWe completed the literature search on May 31, 2021 using PubMed, EMBASE and the Web of Science.
Zhu Zhang, Zhu Zhang, Zhu Zhang, Zhu Zhang, Linfeng Xi, Linfeng Xi, Linfeng Xi, Linfeng Xi, Linfeng Xi, Shuai Zhang, Shuai Zhang, Shuai Zhang, Shuai Zhang, Yunxia Zhang, Yunxia Zhang, Yunxia Zhang, Yunxia Zhang, Guohui Fan, Guohui Fan, Guohui Fan, Guohui Fan, Xincao Tao, Xincao Tao, Xincao Tao, Xincao Tao, Qian Gao, Qian Gao, Qian Gao, Qian Gao, Wanmu Xie, Wanmu Xie, Wanmu Xie, Wanmu Xie, Peiran Yang, Zhenguo Zhai, Zhenguo Zhai, Zhenguo Zhai, Zhenguo Zhai, Chen Wang, Chen Wang, Chen Wang, Chen Wang, Chen Wang, Chen Wang   +43 more
doaj   +1 more source

Predictors of in-hospital mortality in patients with ST-segment elevation myocardial infarction undergoing pharmacoinvasive treatment [PDF]

, 2013
OBJECTIVES: To identify predictors of in-hospital mortality in patients with acute myocardial infarction undergoing pharmacoinvasive treatment. METHODS: This was an observational, prospective study that included 398 patients admitted to a tertiary center
Alves, Claudia Maria Rodrigues, Amaral, Amaury, Barbosa, Adriano Henrique Pereira, Caixeta, Adriano, Carvalho, Antonio Carlos, Falcão, Felipe José de Andrade, Goncalves Junior, Iran, Perez, Fatima Cristina A., Sousa, Jose Marconi Almeida, Souza, José Augusto Marcondes de, Stefanini, Edson, Wilke, Luiz Carlos   +11 more
core   +5 more sources

Tenecteplase versus alteplase for the treatment of acute ischemic stroke: a meta-analysis of randomized controlled trials

Annals of Medicine
Objectives Tenecteplase, a modified variant of alteplase with greater fibrin specificity and longer plasma half-life, may have better efficacy and safety than alteplase in patients with acute ischemic stroke (AIS).
Jian Huang, Hui Zheng, Xianfeng Zhu, Kai Zhang, Xiaofeng Ping   +4 more
doaj   +1 more source

Tenecteplase infusion: The saviour in partially successful thrombolysis of prosthetic heart valve thrombosis

IHJ Cardiovascular Case Reports, 2021
A 20-year-old female, with history of mitral valve replacement presented with recent onset breathlessness. Cine fluoroscopy showed restricted leaflet mobility.
Dr A. Shaheer Ahmed, Dr Shivank Gupta, Dr Anwar Hussain Ansari   +2 more
doaj   +1 more source

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy, Eastwood, Jo-Ann, Gylys, Karen, Meyer, Dawn M, Zivin, Justin A   +4 more
core   +3 more sources

Tenecteplase versus alteplase for acute ischaemic stroke in the elderly patients: a post hoc analysis of the TRACE-2 trial

Stroke and Vascular Neurology
Background The benefit–risk profile of tenecteplase in the elderly patients with acute ischaemic stroke (AIS) is uncertain. We sought to investigate the efficacy and safety of 0.25 mg/kg tenecteplase compared with alteplase for AIS patients aged ≥80 ...
Bruce C V Campbell, Yongjun Wang, Zixiao Li, Yunyun Xiong, Yuesong Pan, Lee H Schwamm, Shuya Li, Mengxing Wang, Na Wu, Liyuan Wang, Manjun Hao, Zhixin Cao, Chunmiao Duan, Shuangzhe Wu   +13 more
doaj   +1 more source

Data science of stroke imaging and enlightenment of the penumbra. [PDF]

, 2015
Imaging protocols of acute ischemic stroke continue to hold significant uncertainties regarding patient selection for reperfusion therapy with thrombolysis and mechanical thrombectomy.
Liebeskind, David S, Nour, May, Scalzo, Fabien   +2 more
core   +2 more sources

Tenecteplase compared to alteplase in real-world outcome: A Swedish Stroke Register study

Upsala Journal of Medical Sciences
Background: Tenecteplase is increasingly used off-label as an alternative to alteplase for ischemic stroke thrombolysis. Our aim was to evaluate the safety of tenecteplase versus alteplase in comprehensive real-world data.
Mikael Skärlund, Signild Åsberg, Marie Eriksson, Erik Lundström   +3 more
doaj   +1 more source

Creation of Tenecteplase-Producing CHO Cell Line Using Site-Specific Integrase from the Phage φC31 [PDF]

Cell Journal, 2010
Objective: The aim of this study was to produce a stable CHO cell line expressing tenecteplase.Materials and Methods: In the first step, the tenecteplase coding sequence was clonedin a pDB2 vector containing attB recognition sites for the phage φC31 ...
Khadijeh Karbalaie, Mohammad Reza Mofid, Mohammad Hossain Nasr Esfahani, Michele P. Calos, Kianoush Dormiani, Pharm, Fereshteh Karamali, Kamran Ghaedi, Mahboobeh Forouzanfar, Yahya Khazaie, Pharm   +8 more
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