Results 61 to 70 of about 7,183 (232)

The safety of enoxaparine use in elderly with acute myocardial infarction [PDF]

, 2007
Background/Aim. Enoxaparin (ENOX), the lowmolecular- weight heparin, used in acute myocardial infarction (AMI) could lead to hemorrhage. The aim of this study was to determine whether bleeding was more often in AMI patients older than 65 or 75 years who ...
Despotović Nebojša, Dimković Siniša, Ilić Marjan, Lončar Goran, Nikolić-Despotović Maja   +4 more
core   +1 more source

Efficacy and safety of tenecteplase for acute ischemic stroke within an extended treatment window: a systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials [PDF]

Journal of Neurocritical Care
Background In acute ischemic stroke (AIS), the treatment window for thrombolytics is 4.5 hours from symptom onset. Tenecteplase, a modified tissue plasminogen activator, may be effective over an extended treatment window (4.5–24 hours).
Hesham Kelani, Mohamed R. Abdelraouf, Hazem Mohamed Salamah, Eli Berglas, Toka Elboraay, Abdelrahman Mahmoud, Mohamed Abugdida, Nadia Albaramony, Ahmed Abd Elazim, Diana Greene-Chandos, Mohammad El-Ghanem, Volodymyr Vulkanov, Artem Sunik, Amit Khaneja, David P. Lerner, Fawaz Al-Mufti   +15 more
doaj   +1 more source

Review of Protocols Used in Ultrasound Thrombolysis [PDF]

, 2017
Objectives: This paper focuses on the review of protocols used in thrombolysis studies with ultrasound. Materials and methods: Data from peer-review articles were acquired.
Damianou, C., Kyriacou, P. A., Papadopoulos, N.   +2 more
core   +1 more source

Tenecteplase Treatment and Thrombus Characteristics Associated With Early Reperfusion: An EXTEND-IA TNK Trials Analysis [PDF]

, 2023
Vignan Yogendrakumar, Leonid Churilov, Prodipta Guha, James Beharry, Peter Mitchell, Timothy Kleinig, Nawaf Yassi, Vincent Thijs, Teddy Y. Wu, Helen Brown, Helen M. Dewey, Tissa Wijeratne, Bernard Yan, Gagan Sharma, Patricia Desmond, Mark Parsons, Geoffrey A. Donnan, Stephen M. Davis, Bruce Campbell, Richard Dowling, Steven Bush, Rebecca Scroop, Mark Brooks, Hamed Asadi, Timothy Ang, Ferdinand Miteff, Christopher Levi, Henry Zhao, Felix Ng, Fana Alemseged, Henry E. Rice, Laetitia de Villiers, Kendal Redmond, David Leggett   +33 more
openalex   +1 more source

Efficacy and Safety of Nerinetide in Acute Ischemic Stroke Patients: A Systematic Review, Meta‐Analysis and Meta Regression

Brain and Behavior, Volume 15, Issue 11, November 2025.
Nerinetide modestly reduced mortality in acute ischemic stroke (RR = 0.86; p = 0.05) without improving functional recovery (mRS, Barthel Index, infarct volume). Safety was comparable to placebo. Further large RCTs are needed to clarify its role and interaction with reperfusion therapies.
Laiba Khurram, Laksh Kumar, Muaz Noor, Faizan Shams, Muhammad Yousuf, Abdullah Ubaid, Jodho Ji, FNU Somdev, FNU Samiullah, Muhammad Junaid Imran, Waqar Malik, Adarsh Raja, Abdullah BS, Biruk Demisse Ayalew, Aayush Chaulagain   +14 more
wiley   +1 more source

Thrombolytic therapy for patients with acute ischemic stroke: systematic review and network meta-analysis of randomized trials

Frontiers in Neurology
ObjectiveTo systematically compare the benefits and risks of all thrombolytic agents (tenecteplase, reteplase, and alteplase) at different doses for thrombolytic therapy in patients with acute ischemic stroke (AIS).BackgroundAlteplase is the cornerstone ...
Li-Chao-Yue Sun, Wen-Shu Li, Wei Chen, Zhao Ren, Chun-Xing Li, Ze Jiang, Le Wang, De-Li Wang, Qing Xie   +8 more
doaj   +1 more source

Influence of the double antiplatelet therapy on patency of the infarct related artery after acute myocardial infarction with ST-segment elevation [PDF]

, 2007
Background/Aim. Most patients with acute myocardial infarction with ST-segment elevation (STEMI) are still treated with pharmacological reperfusion, which is not always successful.
Apostolović Svetlana, Božinović Nenad, Damjanović Miodrag, Janković Ružica, Milenković Dušan, Pavlović Milan, Perišić Zoran, Tomašević Miloje, Đorđević-Radojković Danijela, Šalinger-Martinović Sonja   +9 more
core   +1 more source

To Bridge or Not to Bridge? A Meta‐Analysis of Intravenous Thrombolysis Before Thrombectomy in Large Ischemic Core Strokes

Brain and Behavior, Volume 15, Issue 11, November 2025.
Based on the included 7 studies, in patients with large ischemic core infarcts, IVT before EVT offers no significant clinical or procedural benefit compared to EVT alone. ABSTRACT Background Endovascular thrombectomy (EVT) is the standard treatment for acute ischemic stroke (AIS) caused by large vessel occlusion (LVO).
Abdelrahman Elgharabawi, Mostafa Hossam El Din Moawad, Reham M. Wagih, Yousr Ahmed, Mohammed Elkholy, Ibrahim Serag, Ibraheem M. Alkhawaldeh, Mahmoud Elsayed, Abdelrahman Elkholy, Ahmed Abdelraouf, Obai Yousef, Younes Nabgouri, Mohamed Abouzid   +12 more
wiley   +1 more source

Successful use of intra venous tenecteplase for acute ischemic stroke in pregnancy

eNeurologicalSci
Intravenous thrombolysis (IVT) with tenecteplase or alteplase is the standard of care in, patients with Acute Ischemic Stroke (AIS) presenting within 3–4.5 h. However here, are no established guidelines for such treatment during pregnancy.
Balamurugan Namasivayam, Chitra Sengodan, Lavanya Mohanasundaram, Sathya Chinna Gounder, Madunisha Sivakumar   +4 more
doaj   +1 more source

Comparison between zofenopril and ramipril in combination with acetylsalicylic acid in patients with left ventricular systolic dysfunction after acute myocardial infarction: results of a randomized, double-blind, parallel-group, multicenter, European study (SMILE-4) [PDF]

, 2012
BACKGROUND: Angiotensin-converting enzyme inhibitors (ACEIs) are largely employed for treating patients with left ventricular dysfunction (LVD), but their efficacy may be negatively affected by concomitant administration of acetylsalicylic acid (ASA),
Claudio Borghi, Dragos Vinereanu, Ettore Ambrosioni, Giuseppe Ambrosio, null null, Salvatore Novo   +5 more
core   +1 more source