Results 21 to 30 of about 79,407 (254)

In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. [PDF]

open access: yesPLoS ONE, 2010
Tenofovir gel has entered into clinical trials for use as a topical microbicide to prevent HIV-1 infection but has no published data regarding pre-clinical testing using in vitro and ex vivo models.
Lisa C Rohan   +13 more
doaj   +1 more source

Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring [PDF]

open access: yes, 2018
Objectives: The resistance profiles of patients receiving long-term ART in sub-Saharan Africa have been poorly described. This study obtained a sensitive assessment of the resistance patterns associated with long-term tenofovir-based ART in a ...
Appiah, Lambert T   +9 more
core   +3 more sources

Risk of Hepatocellular Carcinoma With Tenofovir vs Entecavir Treatment for Chronic Hepatitis B Virus

open access: yesJAMA Network Open, 2022
Key Points Question What is the comparative risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus infection receiving tenofovir vs entecavir?
D. Tan   +15 more
semanticscholar   +1 more source

Acquired Fanconi Syndrome from Tenofovir Treatment in a Patient with Hepatitis B

open access: yesCase Reports in Hepatology, 2023
Fanconi syndrome is a rare disease of generalized proximal tubule dysfunction which can be acquired secondary to certain medications, including tenofovir, a commonly used hepatitis B treatment.
Shirley X. Jiang   +2 more
doaj   +1 more source

Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients. [PDF]

open access: yes, 2017
BackgroundThe antiretroviral medication, tenofovir disoproxil fumarate (TDF), is used by most human immunodeficiency virus-infected persons in the United States despite higher risks of chronic kidney disease.
Chen, Ruijun   +7 more
core   +1 more source

Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Two drugs under consideration for inclusion in antiretroviral therapy (ART) regimens for human immunodeficiency virus (HIV) infection are dolutegravir (DTG) and tenofovir alafenamide fumarate (TAF).
W. Venter   +18 more
semanticscholar   +1 more source

TACE versus TACE + entecavir versus TACE + tenofovir in the treatment of HBV associated hepatocellular carcinoma

open access: yesBMC Cancer, 2023
Background At present, there are a variety of antiviral drugs for HBV in clinical practice, but there is no standard scheme for transcatheter arterial chemoembolization(TACE) combined with antiviral drugs. The aim of this study was to investigate whether
Haohao Lu   +3 more
doaj   +1 more source

Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years. [PDF]

open access: yes, 2011
The latest World Health Organization guidelines recommend replacing stavudine with tenofovir or zidovudine in first-line antiretroviral therapy in resource-limited settings.
Birkus   +12 more
core   +2 more sources

The effect of tenofovir on vitamin D metabolism in HIV-infected adults is dependent on sex and ethnicity.

open access: yesPLoS ONE, 2012
BackgroundTenofovir has been associated with renal phosphate wasting, reduced bone mineral density, and higher parathyroid hormone levels. The aim of this study was to carry out a detailed comparison of the effects of tenofovir versus non-tenofovir use ...
Karen Klassen   +5 more
doaj   +1 more source

A Review and Clinical Understanding of Tenofovir: Tenofovir Disoproxil Fumarate versus Tenofovir Alafenamide

open access: yesJournal of the International Association of Providers of AIDS Care, 2020
HIV is a serious chronic medical condition. Significant improvements in antiretroviral therapy have led to a transformation in its management. No curative treatment is available for HIV, and lifelong therapy is required with a combination of agents to ...
Chanie Wassner   +2 more
semanticscholar   +1 more source

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