Results 31 to 40 of about 79,407 (254)

An expert consensus for the management of chronic hepatitis B in Asian Americans. [PDF]

open access: yes, 2018
BACKGROUND: Hepatitis B virus (HBV) infection is common with major clinical consequences. In Asian Americans, the HBsAg carrier rate ranges from 2% to 16% which approximates the rates from their countries of origin.
Abbas   +173 more
core   +2 more sources

Review article: switching patients with chronic hepatitis B to tenofovir alafenamide—a review of current data

open access: yesAlimentary Pharmacology and Therapeutics, 2022
The nucleos(t)ide analogues (NAs) entecavir (ETV), tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) are preferred treatment options for patients with chronic hepatitis B infection (CHB).
Y. Lim   +11 more
semanticscholar   +1 more source

The Role of Drug Transporters in the Kidney: Lessons from Tenofovir

open access: yesFrontiers in Pharmacology, 2014
Tenofovir disoproxil fumarate, the prodrug of nucleotide reverse transcriptase inhibitor tenofovir, shows high efficacy and relatively low toxicity in HIV patients.
Darren Michael Moss   +2 more
doaj   +1 more source

Excess Weight Gain With Integrase Inhibitors and Tenofovir Alafenamide: What Is the Mechanism and Does It Matter?

open access: yesOpen Forum Infectious Diseases, 2021
Numerous studies have detected a greater likelihood of excess weight gain with specific antiretrovirals (ARVs), particularly tenofovir alafenamide and integrase inhibitors, as compared with other agents and classes.
Brian R Wood, G. Huhn
semanticscholar   +1 more source

Guides concerning tenofovir exposure via breastfeeding: A comparison of drug dosages by developmental stage

open access: yesInternational Journal of Infectious Diseases, 2019
Tenofovir disoproxil fumarate (TDF) is a prodrug of tenofovir, and after being administered orally, it converts to tenofovir in the blood. With the increasing use of TDF in women for treatment and prevention of mother-to-child transmission (MTCT) of both
Xiaotong Hu, Liming Wang, Fujie Xu
doaj   +1 more source

[Tenofovir nephrotoxicity].

open access: yesNephrologie & therapeutique, 2016
Le ténofovir est le seul inhibiteur nucléotidique de la transcriptase inverse du virus de l’immunodéficience humaine (VIH) actuellement commercialisé. Bien qu’il s’agisse d’un médicament globalement bien toléré prescrit à des millions de patients – sans surveillance particulière dans les pays en voie de développement – une néphrotoxicité considérable a
Isnard-Bagnis, Corinne   +3 more
openaire   +2 more sources

Effectiveness of dolutegravir-based regimens as either first-line or switch antiretroviral therapy: data from the Icona cohort [PDF]

open access: yes, 2019
Introduction: Concerns about dolutegravir (DTG) tolerability in the real-life setting have recently arisen. We aimed to estimate the risk of treatment discontinuation and virological failure of DTG-based regimens from a large cohort of HIV-infected ...
Abeli C.   +155 more
core   +4 more sources

Impact of small body weight on tenofovir-associated renal dysfunction in HIV-infected patients: a retrospective cohort study of Japanese patients. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Treatment with tenofovir is sometimes associated with renal dysfunction. Limited information is available on this side effect in patients with small body weight, although the use of tenofovir will spread rapidly in Asia and Africa, where ...
Takeshi Nishijima   +13 more
doaj   +1 more source

Differential binding of tenofovir and adefovir to reverse transcriptase of hepatitis B virus. [PDF]

open access: yesPLoS ONE, 2014
Resistance of the reverse transcriptase (RT) of hepatitis B virus (HBV) to the tenofovir nucleotide drug has not been observed since its introduction for treatment of hepatitis B virus (HBV) infection in 2008. In contrast, frequent viral breakthrough and
Formijn J van Hemert   +2 more
doaj   +1 more source

Effectiveness and safety of oral HIV preexposure prophylaxis for all populations. [PDF]

open access: yes, 2016
ObjectivePreexposure prophylaxis (PrEP) offers a promising new approach to HIV prevention. This systematic review and meta-analysis evaluated the evidence for use of oral PrEP containing tenofovir disoproxil fumarate as an additional HIV prevention ...
Baggaley, Rachel   +8 more
core   +2 more sources

Home - About - Disclaimer - Privacy