Results 61 to 70 of about 19,810 (202)

A United States HIV provider survey of antiretroviral therapy management in people living with HIV with co-occurring conditions

AIDS Research and Therapy
Introduction Simplified HIV treatment guidelines favor integrase strand transfer inhibitors (INSTIs). However, non-infectious comorbidities and co-occurring conditions (i.e.
Sonya Krishnan, Marina B. Martinez Rivera, Christopher K. Lippincott, Maunank Shah   +3 more
doaj   +1 more source

Longitudinal changes in readily available inflammatory markers before and after switching to integrase inhibitor‐based antiretroviral therapy in Virologically suppressed people living with HIV: A Nationwide real‐world cohort study

HIV Medicine, EarlyView.
Abstract Background Persistent immune activation and systemic inflammation remain key features of chronic HIV infection despite sustained virological suppression under antiretroviral therapy (ART), contributing to excess non‐AIDS morbidity and mortality.
Stelios Assimakopoulos, Achilleas Stamoulopoulos, Mina Psichogiou, Varvara Vasalou, Vasileios Papastamopoulos, Antonis Papadopoulos, Georgios Adamis, Maria Chini, Simeon Metallidis, Georgios Loizos, Lydia Leonidou, Helen Sambatakou, Markos Marangos, Diamantis Kofteridis, Giota Touloumi, on behalf of AMACS, G. Adamis, M. Chini, G. Chrysos, M. Marangos, O. Katsarou, D. Kofteridis, S. Metallidis, P. Panagopoulos, N. Pantazis, A. Papadopoulos, V. Paprizos, V. Papastamopoulos, M. Psichogiou, H. Sambatakou, NV. Sipsas, G. Touloumi, G. Touloumi, N. Pantazis, C. Thomadakis, A Stamoulopoulos, A Papadopoulos, A Antoniadou, C Protopapas, D Kavatha, G Chrysos, T Nitsotolis, M Psichogiou, E Mastrogianni, G Adamis, M Astriti, MN Marangos, L Leonidou, O Katsarou, A Kouramba, NV Sipsas, A Kontos, D Basoulis, M Chini, G Tsekes, N Mangafas, S Metallidis, O Tsachouridou, Τ Chrysanthidis, V Paparizos, V Vasalou, S Kourkounti, H Sambatakou, V Papastamopoulos, G Lourida, P Panagopoulos, V Petrakis, D Kofteridis, K Alexakis, V Malikidis, H Gogos, M Psichogiou   +71 more
wiley   +1 more source

Health care providers' decision-making and early adoption of tenofovir alafenamide for HIV preexposure prophylaxis: An inductive qualitative study.

PLoS ONE
BackgroundOver the past several years, there have been several changes affecting the available options for oral HIV preexposure prophylaxis, including approvals for tenofovir alafenamide with emtricitabine in 2019 and a generic formulation of tenofovir ...
Elisabeth Merchant, Patricia Solleveld, Kevin Gibas, Douglas Krakower   +3 more
doaj   +1 more source

Efficacy and safety of the regimens containing tenofovir alafenamide versus tenofovir disoproxil fumarate in fixed-dose single-tablet regimens for initial treatment of HIV-1 infection: A meta-analysis of randomized controlled trials

International Journal of Infectious Diseases, 2020
Background: Tenofovir disoproxil fumarate (TDF) can cause renal and bone toxicity, which is associated with high plasma tenofovir concentrations in antiretroviral treatment of HIV-1 infected patients.
Xingbao Tao, Yanqiu Lu, Yihong Zhou, Lvlang Zhang, Yaokai Chen   +4 more
doaj   +1 more source

Understanding community questions about HIV pre‐exposure prophylaxis (PrEP): A thematic analysis of reddit threads to inform development of an AI chatbot for PrEP education

HIV Medicine, EarlyView.
Abstract Background Despite growing availability of HIV pre‐exposure prophylaxis (PrEP), many potential users turn to online forums for advice and information collection. These forums provide a window into real‐world questions, concerns and misinformation.
Alexandar Vincent‐Paulraj, William Wood, Catia Marzolini, Justin Chiong, Daryl Hodge, Sara Gibbons, Daniel Seddon, Jasmine Martin, Saye Khoo, Lauren E. Waker   +9 more
wiley   +1 more source

Additional file 3 of Effect of sofosbuvir-based DAAs on changes in lower-density lipoprotein in HCV patients: a systematic review and meta-analysis

, 2021
Additional file 3: Fig. S3. Chemicalstructures of tenofovir alafenamide, sofosbuvir, and tenofovir disoproxilfumarate.
Ming-Chih Hou (383484), Ying-Wen Wang (404816), Wei-Ping Lee (11464170), Yi-Hsiang Huang (115190), Keng-Hsin Lan (449370)   +4 more
core   +1 more source

Pharmacist's role in managing drug–drug interactions in people with HIV receiving antiretroviral therapy or HIV pre‐exposure prophylaxis: A focus on polypharmacy and transitions of care in the United States

British Journal of Clinical Pharmacology, EarlyView.
Shawnalyn W. Sunagawa, Elizabeth M. Sherman, Melissa Badowski, David B. Cluck, Spencer H. Durham, Joshua P. Havens, Emily Huesgen, Justin K. Ma, Roxane Rohani, Eric G. Sahloff, Kristy M. Shaeer, Radhika S. Polisetty   +11 more
wiley   +1 more source

Clinical Application of Artificial Intelligence in the Management of Chronic Hepatitis B

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Chronic hepatitis B (CHB) burdens the healthcare system, affecting millions of individuals worldwide with a potential progression to complications such as cirrhosis and hepatocellular carcinoma (HCC). The World Health Organization launched the chronic viral hepatitis elimination plan which aimed to eliminate chronic hepatitis B virus by 2030 ...
Jimmy Che‐To Lai, Xiaoqing Guo, Xinyan Zong, Nana Peng, Terry Cheuk‐Fung Yip, Vincent Wai‐Sun Wong, Pong‐Chi Yuen, Grace Lai‐Hung Wong   +7 more
wiley   +1 more source

Table1_Effectiveness and safety of tenofovir amibufenamide and its comparison with tenofovir alafenamide in patients with chronic hepatitis B: results from a retrospective real-world study.docx

, 2023
Background/aim: Tenofovir amibufenamide (TMF) has shown potent antiviral efficacy in randomized clinical studies. This study aimed to reveal the effectiveness and safety of tenofovir amibufenamide in the real world and compared tenofovir amibufenamide to
Menglan Wang (2810128), Fada Wang, Yujing Li (216269), Menglan Wang, Dongmei Zhang (89650), Yachao Tao (12157872), Fada Wang (16002305), Lanqing Li, Jing Zhou (168494), Enqiang Chen (2810131), Dongmei Zhang, Lanqing Li (11505488), Yachao Tao, Yujing Li, Jing Zhou, Enqiang Chen   +15 more
core   +1 more source

An Efficient Synthesis of Tenofovir (PMPA): A Key Intermediate Leading to Tenofovir-Based HIV Medicines [PDF]

, 2020
: Herein, we report further improvements to the synthesis of tenofovir 1, the precursor to tenofovir disoproxil fumarate and tenofovir alafenamide fumarate.
Brenden, Herrera, Rodger W., Stringham, Jule-Phillip, Dietz, B. Frank, Gupton, D. Tyler, McQuade, Cheryl, Peck, Flavio S. P., Cardoso, Anthony, J. Arduengo III, Andrew C., Yue, Dinesh J., Paymode, David R., Snead, Brenden, Derstine, John W., Tomlin, Till, Opatz   +13 more
core   +2 more sources