A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes. [PDF]
PLoS ONE, 2010 The first Swiss human embryonic stem cell (hESC) line, CH-ES1, has shown features of a malignant cell line. It originated from the only single blastomere that survived cryopreservation of an embryo, and it more closely resembles teratocarcinoma lines ...
Outi Hovatta +14 more
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Exploring the Anticancer Properties of 4-Phenylthiazole-Based Ru(II) and Os(II) Metallacycles Featuring 1-Methylimidazole as N-Donor Functionality [PDF]
Bioinorganic Chemistry and ApplicationsTen organometallic complexes of the general formula [M(p-cymene)thiCΛNMeIm]NO3 (M = Ru, Os; MeIm = 1-methylimidazole, thi = 4-phenylthiazole) differing in their substituents on the 4-phenylthiazole scaffold were prepared and characterized by standard ...
Paul Getreuer +12 more
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23-Year-Old Male with Testis Cancer with Spontaneous Ruptured Teratocarcinoma and No History of Trauma: A Case Report [PDF]
Case Reports in Oncology, 2023 Teratocarcinoma is one type of testis cancer that can be represented in the youth population and usually shows itself with swelling of the testis and edema and a rise of BHCG and alpha-fetoprotein, but spontaneous rupture is a rare manifestation.
Fardin Asgari +3 more
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The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells.
PLoS ONE, 2019 Human endogenous retroviruses are remnants of ancient germline infections that make up approximately 8% of the modern human genome. The HERV-K (HML-2) family is one of the most recent entrants into the human germline, these viruses appear to be ...
Susana M Chan +6 more
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Primary CNS Teratocarcinoma [PDF]
Frontiers in Neurology, 2012 Primary central nervous system (CNS) teratomas are rare tumors that consist of all three germ cell layers. We describe a young man with a primary malignant CNS teratocarcinoma presenting as leptomeningeal carcinomatosis.
Danilo eVitorovic +4 more
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Digital Twin Meets the Bench: Natural Compounds Reshape the Ovarian Cancer Microenvironment [PDF]
BiomedicinesBackground: Malignant ovarian tumours are most often detected at an advanced stage, when peritoneal dissemination across abdominal organs is already present.
Anna Kleczka +2 more
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Comparative immunohistochemical characterisation of a teratoma in a domestic duck (Anas platyrhynchos) and a teratocarcinoma in a muscovy duck (Cairina moschata) [PDF]
Acta Veterinaria ScandinavicaBackground Neoplasms consisting of two or more germinal layers are classified as teratomas if benign or as teratocarcinomas if malignant. Teratomas are rare tumours occurring in a wide range of species including mammals, birds and reptiles and only a few
Deborah Johanna Eikelberg +5 more
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Teratocarcinoma Formation in Embryonic Stem Cell-Derived Neural Progenitor Hippocampal Transplants
Cell Transplantation, 2012 Embryonic stem cells (ESCs) hold great therapeutic potential due to their ability to differentiate into cells of the three primary germ layers, which can be used to repopulate disease-damaged tissues. In fact, two cell therapies using ESC derivatives are
Noélle D. Germain +5 more
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International Journal of Nanomedicine, 2017 Jae Woong Han, Sangiliyandi Gurunathan, Yun-Jung Choi, Jin-Hoi Kim Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Center (SRC), Konkuk University, Seoul, Republic of Korea Background: Silver nanoparticles (AgNPs) exhibit
Han JW, Gurunathan S, Choi YJ, Kim JH
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Viruses, 2015 Human endogenous retrovirus (HERV-K (HML-2)) proviruses are among the few endogenous retroviral elements in the human genome that retain coding sequence.
Neeru Bhardwaj +3 more
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