Results 51 to 60 of about 10,766 (249)

Overexpression of the cellular retinoic acid binding protein-I (CRABP- I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells

Journal of Cell Biology, 1991
Treatment of F9 teratocarcinoma stem cells with retinoic acid (RA) causes their irreversible differentiation into extraembryonic endoderm. To elucidate the role of the cellular retinoic acid binding protein-I (CRABP-I) in this differentiation process, we
John E. Boylan
semanticscholar   +1 more source

The Role of Hemoglobin in Temporomandibular Joint Osteoarthritis and the Therapeutic Potential of Hydroxyurea

International Journal of Dentistry, Volume 2026, Issue 1, 2026.
Background Temporomandibular joint osteoarthritis (TMJ OA) is characterized by articular cartilage degeneration involving chondrocyte loss and matrix degradation. However, the underlying mechanisms remain elusive. Hemoglobin (HB) has been identified in chondrocytes and is closely associated with cell survival.
Min Hui, Zhihua Xu, Qinghua Li, Ying Zhan, Yuqian Shi, Fan Wu, Lei Lu, Mian Zhang, Hongxu Yang, Shibin Yu, Jing Zhang, Hannah Wesley   +11 more
wiley   +1 more source

Revisiting Clonal Evolution Through the Light of Retrotransposons

BioEssays, Volume 47, Issue 12, December 2025.
We propose integrating retrotransposons into the clonal evolution model of cancer. Retrotransposons can modulate cancer cell fitness, potentially influencing clonal dynamics. They might also induce lineage violations via cell fusion or horizontal transfer.
Anaïs Lamoureux, Emilie Elvira‐Matelot, Françoise Porteu, Lucie Laplane   +3 more
wiley   +1 more source

Western blot data using two distinct anti-O-GlcNAc monoclonal antibodies showing unique glycosylation status on cellular proteins under 2-deoxy-d-glucose treatment

Data in Brief, 2017
Protein modification by O-linked N-acetylglucosamine (O-GlcNAcylation) is one of the post transcriptional modifications occurring on cellular proteins.
Tetsuya Okuda
doaj   +1 more source

Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents—A Novel Polymer Formulation for Anticancer Therapy

Pharmaceuticals, 2023
Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents.
Yvonne Lerchbammer-Kreith, Michaela Hejl, Nadine S. Sommerfeld, Xian Weng-Jiang, Uchechukwu Odunze, Ryan D. Mellor, David G. Workman, Michael A. Jakupec, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Mathea S. Galanski, Bernhard K. Keppler   +11 more
doaj   +1 more source

Dynamic Compression Improves Chondrogenesis in the Tissue Engineered Model of Cartilage

Biotechnology and Bioengineering, Volume 122, Issue 9, Page 2574-2591, September 2025.
ABSTRACT Hyaline cartilage is a dense avascular tissue with low regenerative potential, present at the ends of the diarthrodial joints and in the cartilage growth plate. Skeletal diseases often result from extracellular changes in this tissue; however, studies of these are hindered by the tissue complexity, the difficulty in obtaining human material ...
Marc V. Farcasanu, Thais de las Heras Ruiz, Francesca M. Johnson de Sousa Brito, Jamie Soul, Jonathan Coxhead, Matthew J. German, David A. Young, Ana M. Ferreira‐Duarte, Katarzyna A. Piróg   +8 more
wiley   +1 more source

Mature cystic teratoma arising from the fimbrial end of the left fallopian tube. a case report

Journal of International Medical Research, 2020
We present a rare case of a woman with a mass containing soft tissue, fat, and calcified components attached to the fimbrial end of the left fallopian tube.
Szu-Yuan Chou, Chi-Huang Chen, Shang-Yu Tzeng, Yu-Ching Wen, Ming-Cheih Lin, Chii-Ruey Tzeng   +5 more
doaj   +1 more source

Of mice and men: teratomas and teratocarcinomas. [PDF]

Collegium antropologicum, 2006
Teratomi i teratokarcinomi su tumori koji se sastoje od tkivnih derivata svih triju zametnih listića. Moguće ih je inducirati transplantacijom animalnih zametaka u ektopični mikrookoliš. Razvoj malignog teratokarcinoma ovisi o stadiju razvoja zametka, species-specifičnosti te imunološkoj kompetenciji domaćina.
Bulić-Jakuš, Floriana, Ulamec, Monika, Vlahović, Maja, Sinčić, Nino, Katušić, Ana, Jurić-Lekić, Gordana, Šerman, Ljiljana, Krušlin, Božo, Belicza, Mladen   +8 more
openaire   +3 more sources

The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells.

Journal of Biological Chemistry, 1992
The CRABP-I and CRABP-II proteins are high affinity cytoplasmic retinoic acid-binding proteins. In undifferentiated F9 teratocarcinoma stem cells, only the CRABP-I protein is expressed at detectable levels. We have previously shown that overexpression of
J. Boylan, L. Gudas
semanticscholar   +1 more source

Advances and Challenges in Pluripotent Stem Cell‐Based Whole‐Cell Vaccines for Cancer Treatment

Medicine Bulletin, Volume 1, Issue 1, Page 60-76, June 2025.
ABSTRACT In recent decades, an unexpected application of pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), as a novel source for whole‐cell vaccines (WCVs) against cancer has attracted attention in the field of tumor immunotherapy.
Guoyue Wan, Jian‐Dong Huang, Ren‐He Xu, Meiling Jin   +3 more
wiley   +1 more source