Results 61 to 70 of about 1,927 (151)

An Update on Antitumor Efficacy of Catechins: From Molecular Mechanisms to Clinical Applications

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
This article explores the potential of catechins, particularly (−)‐epigallocatechin‐3‐gallate (EGCG) as natural compounds with anticancer effects. Catechins, abundant in plants like green tea, have shown promise in modulating key processes in carcinogenesis, including apoptosis, cell cycle arrest, and angiogenesis. The review emphasizes their potential
Patrick Valere Tsouh Fokou, Boniface Kamdem Pone, Regina Appiah‐Oppong, Vincent Ngouana, Issakou Bakarnga‐Via, David Ntieche Woutouoba, Valerie Flore Donfack Donkeng, Lauve Rachel Tchokouaha Yamthe, Fabrice Fekam Boyom, Dilek Arslan Ateşşahin, Javad Sharifi‐Rad, Daniela Calina   +11 more
wiley   +1 more source

Comparative immunohistochemical characterisation of a teratoma in a domestic duck (Anas platyrhynchos) and a teratocarcinoma in a muscovy duck (Cairina moschata)

Acta Veterinaria Scandinavica
Background Neoplasms consisting of two or more germinal layers are classified as teratomas if benign or as teratocarcinomas if malignant. Teratomas are rare tumours occurring in a wide range of species including mammals, birds and reptiles and only a few
Deborah Johanna Eikelberg, Melanie Stoff, Martin Peters, Marko Legler, Ingo Gerhauser, Peter Wohlsein   +5 more
doaj   +1 more source

Testis: Teratocarcinoma, Choriocarcinoma

, 1900
Teratocarcinoma with choriocarcinoma of testis. Testis is replaced by tumor so that no normal testis is visible.
MUSC Department of Pathology and Laboratory Medicine
core  

TDP‐43/ALKBH5‐mediated m6A modification of CDC25A mRNA promotes glioblastoma growth by facilitating G1/S cell cycle transition

MedComm, Volume 6, Issue 3, March 2025.
In this study, TDP‐43 interacts with ALKBH5 and promotes its binding to CDC25A pre‐mRNA in fast‐growing GBM cells. TDP‐43/ALKBH5 complex demethylates CDC25A pre‐mRNA, inhibiting its exon 6 skipping and preserving the expression of the oncogenic isoform CDC25A‐1, thereby promoting G1/S phase transition and growth of GBM cells.
Yunxiao Zhang, Sidi Xie, Weizhao Li, Junwei Gu, Xi‐an Zhang, Bowen Ni, Ziyu Wang, Runwei Yang, Haimin Song, Yaxuan Zhong, Peiting Huang, Jinyao Zhou, Yongfu Cao, Jing Guo, Yawei Liu, Songtao Qi, Hai Wang   +16 more
wiley   +1 more source

Cytotoxic activity of pyrimethanil on human testicular teratocarcinoma NT2/D1 cells

Heliyon
Fungicides are widely used in the agricultural sector to ensure a safer and larger crop yields. Nevertheless, they represent potentially harmful agents for the environment and living organisms.
Danijela Stanisavljević Ninković, Andrijana Lazić, Milena Aleksić Lilić, Marija Schwirtlich, Perica Vasiljević, Isidora Petrović, Milena Stevanović, Dejan Stojković   +7 more
doaj   +1 more source

In Vitro Engineered ECM‐incorporated Hydrogels for Osteochondral Tissue Repair: A Cell‐Free Approach

Advanced Healthcare Materials, Volume 14, Issue 4, February 7, 2025.
Figure highlights the fabrication process of the osteogenic and chondrogenic decellularized extracellular matrix that can be used for repairing osteochondral defects. 3D osteochondral plugs containing GelMA and the bioactive decellularized extracellular matrix can be prepared by 3D printing.
Ali Coyle, Aishik Chakraborty, Jiaqi Huang, Yasmeen Shamiya, Wei Luo, Arghya Paul   +5 more
wiley   +1 more source

The overexpression of SOX2 affects the migration of human teratocarcinoma cell line NT2/D1

Anais da Academia Brasileira de Ciências, 2015
The altered expression of the SOX2 transcription factor is associated with oncogenic or tumor suppressor functions in human cancers. This factor regulates the migration and invasion of different cancer cells.
DANIJELA DRAKULIC, JELENA MARJANOVIC VICENTIC, MARIJA SCHWIRTLICH, JELENA TOSIC, ALEKSANDAR KRSTIC, ANDRIJANA KLAJN, MILENA STEVANOVIC   +6 more
doaj   +1 more source

Process‐Dependent Variations in the Proliferation of Myoblasts, Fibroblasts and Chondrocytes on Laser‐Sintered Polypropylene

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 2, February 2025.
ABSTRACT Additively manufactured polyolefins find broad applications in medical engineering, enabling the manufacturing of patient‐specific geometries. For investigating the influence of processing conditions of laser sintered locally macroporous polypropylene substrates, the response of myoblasts, chondrocytes, and fibroblasts has been characterized ...
R. Detsch, S. Schlicht, Q. Nawaz, A. R. Boccaccini, D. Drummer   +4 more
wiley   +1 more source

Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre‐Hypertrophic Chondrocytes

Journal of Cellular Physiology, Volume 240, Issue 1, January 2025.
ABSTRACT The growth plate is the primary site of longitudinal bone growth with chondrocytes playing a pivotal role in endochondral bone development. Chondrocytes undergo a series of differentiation steps, resulting in the formation of a unique hierarchical columnar structure comprising round, proliferating, pre‐hypertrophic, and hypertrophic ...
Kenji Hata, Kanta Wakamori, Akane Hirakawa‐Yamamura, Sachi Ichiyama‐Kobayashi, Masaya Yamaguchi, Daisuke Okuzaki, Yoshifumi Takahata, Tomohiko Murakami, Narikazu Uzawa, Takashi Yamashiro, Riko Nishimura   +10 more
wiley   +1 more source

Teratocarcinoma Cells as Vehicles for Introducing Specific Mutant Mitochondrial Genes into Mice

, 1978
TERATOCARCINOMA CELLS AS VEHICLES FOR INTRODUCING SPECIFIC MUTANT MITOCHONDRIAL GENES INTO MICE Teratocarcinoma Cells as Vehicles for Introducing Specific Mutant Mitochondrial Genes into Mice (75) (-
Watanabe, Tomomasa Michael J. Dewey Beatrice Mintz
core   +1 more source