Results 71 to 80 of about 14,185 (219)

Expression of Chrna9 is regulated by Tbx3 in undifferentiated pluripotent stem cells

Scientific Reports, 2023
It was reported that nicotinic acetylcholine receptor (nAChR)-mediated signaling pathways affect the proliferation and differentiation of pluripotent stem cells. However, detail expression profiles of nAChR genes were unrevealed in these cells.
Takashi Yazawa, Yoshitaka Imamichi, Takeshi Kitano, Mohammad Sayful Islam, Md. Rafiqul Islam Khan, Satoru Takahashi, Toshio Sekiguchi, Nobuo Suzuki, Akihiro Umezawa, Junsuke Uwada   +9 more
doaj   +1 more source

Process‐Dependent Variations in the Proliferation of Myoblasts, Fibroblasts and Chondrocytes on Laser‐Sintered Polypropylene

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 2, February 2025.
ABSTRACT Additively manufactured polyolefins find broad applications in medical engineering, enabling the manufacturing of patient‐specific geometries. For investigating the influence of processing conditions of laser sintered locally macroporous polypropylene substrates, the response of myoblasts, chondrocytes, and fibroblasts has been characterized ...
R. Detsch, S. Schlicht, Q. Nawaz, A. R. Boccaccini, D. Drummer   +4 more
wiley   +1 more source

Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]

, 1999
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Prelle, Katja, Vassiliev, Ivan M., Vassilieva, Svetlana G., Wobus, Anna M., Wolf, Eckhard   +4 more
core   +1 more source

Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre‐Hypertrophic Chondrocytes

Journal of Cellular Physiology, Volume 240, Issue 1, January 2025.
ABSTRACT The growth plate is the primary site of longitudinal bone growth with chondrocytes playing a pivotal role in endochondral bone development. Chondrocytes undergo a series of differentiation steps, resulting in the formation of a unique hierarchical columnar structure comprising round, proliferating, pre‐hypertrophic, and hypertrophic ...
Kenji Hata, Kanta Wakamori, Akane Hirakawa‐Yamamura, Sachi Ichiyama‐Kobayashi, Masaya Yamaguchi, Daisuke Okuzaki, Yoshifumi Takahata, Tomohiko Murakami, Narikazu Uzawa, Takashi Yamashiro, Riko Nishimura   +10 more
wiley   +1 more source

Cytotoxic activity of pyrimethanil on human testicular teratocarcinoma NT2/D1 cells

Heliyon
Fungicides are widely used in the agricultural sector to ensure a safer and larger crop yields. Nevertheless, they represent potentially harmful agents for the environment and living organisms.
Danijela Stanisavljević Ninković, Andrijana Lazić, Milena Aleksić Lilić, Marija Schwirtlich, Perica Vasiljević, Isidora Petrović, Milena Stevanović, Dejan Stojković   +7 more
doaj   +1 more source

The overexpression of SOX2 affects the migration of human teratocarcinoma cell line NT2/D1

Anais da Academia Brasileira de Ciências, 2015
The altered expression of the SOX2 transcription factor is associated with oncogenic or tumor suppressor functions in human cancers. This factor regulates the migration and invasion of different cancer cells.
DANIJELA DRAKULIC, JELENA MARJANOVIC VICENTIC, MARIJA SCHWIRTLICH, JELENA TOSIC, ALEKSANDAR KRSTIC, ANDRIJANA KLAJN, MILENA STEVANOVIC   +6 more
doaj   +1 more source

Identification of new SOX2OT transcript variants highly expressed in human cancer cell lines and down regulated in stem cell differentiation [PDF]

, 2016
Long non-coding RNAs are manifested as a new paradigm of molecular effectors in a wide range of human diseases. Human SOX2 overlapping transcript (SOX2OT) gene can generate six lncRNA transcript variants which are functionally assumed to be correlated ...
Ghanei, M., Mowla, S.J., Saghaeian Jazi, M., Samaei, N.M., Shadmehr, M.B.   +4 more
core  

Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]

, 2010
Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica, Dumitrascu, Rio, Eickelberg, Oliver, Grimminger, Friedrich, Königshoff, Melanie, Reiter, Rudolf, Schermuly, Ralph Theo, Seeger, Werner, Udalov, Sergey   +8 more
core   +1 more source

From Bench to Bedside: The Evolving Landscape of Stem Cell Therapies for Stroke Rehabilitation

Stem Cells International, Volume 2025, Issue 1, 2025.
Globally, stroke stands as a principal cause of death and disability, presenting formidable challenges in rehabilitation. Conventional therapeutic modalities often fail to restore functional capabilities fully, underscoring the need for innovative treatment strategies.
Daniel Waszczuk, Shrivats Manikandan, Varsha Manikandan, Erian Stone, Shannon Buehre, Steiv Shore, Manikandan Panchatcharam, Sumitra Miriyala, Alain Chapel   +8 more
wiley   +1 more source

Giant teratocarcinoma of anterosuperior mediastinum

CorSalud, 2019
Germ cell tumors are not so frequent; among them, teratomas are most common in the mediastinal location. Teratomas in young men are usually malignant (teratocarcinoma), with a gender ratio of 13.5:1, and an average age of 26 years.
Gustavo de J. Bermúdez Yera, Nazaret Argueta Cáceres, Ernesto Chaljub Bravo, Rodolfo Morales Valdés   +3 more
doaj