Results 71 to 80 of about 18,230 (245)

Identification of new SOX2OT transcript variants highly expressed in human cancer cell lines and down regulated in stem cell differentiation [PDF]

, 2016
Long non-coding RNAs are manifested as a new paradigm of molecular effectors in a wide range of human diseases. Human SOX2 overlapping transcript (SOX2OT) gene can generate six lncRNA transcript variants which are functionally assumed to be correlated ...
Ghanei, M., Mowla, S.J., Saghaeian Jazi, M., Samaei, N.M., Shadmehr, M.B.   +4 more
core  

ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells.

Genes & Development, 1999
Human ELAV proteins are implicated in cell growth and differentiation via regulation of mRNA expression in the cytoplasm. In human embryonic teratocarcinoma (hNT2) cells transfected with the human neuronal ELAV-like protein, Hel-N1, neurites formed, yet ...
D. Antic, Ning Lu, J. Keene
semanticscholar   +1 more source

Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre‐Hypertrophic Chondrocytes

Journal of Cellular Physiology, Volume 240, Issue 1, January 2025.
ABSTRACT The growth plate is the primary site of longitudinal bone growth with chondrocytes playing a pivotal role in endochondral bone development. Chondrocytes undergo a series of differentiation steps, resulting in the formation of a unique hierarchical columnar structure comprising round, proliferating, pre‐hypertrophic, and hypertrophic ...
Kenji Hata, Kanta Wakamori, Akane Hirakawa‐Yamamura, Sachi Ichiyama‐Kobayashi, Masaya Yamaguchi, Daisuke Okuzaki, Yoshifumi Takahata, Tomohiko Murakami, Narikazu Uzawa, Takashi Yamashiro, Riko Nishimura   +10 more
wiley   +1 more source

Cervical mature teratoma 17 years after initial treatment of testicular teratocarcinoma: report of a late relapse

World Journal of Surgical Oncology, 2007
Background Late relapses of testicular germ cell tumor are uncommon. We report a case of cervical mature teratoma appeared 17 years after treatment of testicular teratocarcinoma.
Alavion Mina, Omranipour Ramesh
doaj   +1 more source

Tumor-targeting properties of novel immunocytokines based on murine IL1β and IL6 [PDF]

, 2017
There is an increasing biotechnological interest in ‘arming' therapeutic antibodies with bioactive payloads. Many antibody-cytokine fusion proteins (immunocytokines) have been described and some of these biopharmaceuticals have progressed to clinical ...
Hess, Christian, Neri, Dario
core  

Effects of selegiline, a monoamine oxidase B inhibitor, on differentiation of P19 embryonal carcinoma stem cells, into neuron-like cells [PDF]

, 2011
Selegiline, the irreversible inhibitor of monoamine oxidase B (MAO-B), is currently used to treat Parkinson's disease. However, the mechanism of action of selegiline is complex and cannot be explained solely by its MAO-B inhibitory action.
Bakhshalizadeh, Shabnam., Esmaeili, Fariba., Houshmand, Fariba., Saedi-Marghmaleki, Mojtaba., shirzad, Hedayatollah.   +4 more
core   +1 more source

Expression of Chrna9 is regulated by Tbx3 in undifferentiated pluripotent stem cells

Scientific Reports, 2023
It was reported that nicotinic acetylcholine receptor (nAChR)-mediated signaling pathways affect the proliferation and differentiation of pluripotent stem cells. However, detail expression profiles of nAChR genes were unrevealed in these cells.
Takashi Yazawa, Yoshitaka Imamichi, Takeshi Kitano, Mohammad Sayful Islam, Md. Rafiqul Islam Khan, Satoru Takahashi, Toshio Sekiguchi, Nobuo Suzuki, Akihiro Umezawa, Junsuke Uwada   +9 more
doaj   +1 more source

Proadrenomedullin NH(2)-terminal 20 peptide (PAMP) and adrenomedullin bind to teratocarcinoma cells. [PDF]

, 2000
Proadrenomedullin NH(2-)terminal 20 peptide (PAMP) and adrenomedullin (ADM) bind to teratocarcinoma cells. The effects of PAMP and ADM on teratocarcinoma cells were investigated.
Coy, D. (D.), Cuttitta, F. (Frank), Montuenga-Badia, L.M. (Luis M.), Moody, T.W. (T.W.)   +3 more
core   +1 more source

From Bench to Bedside: The Evolving Landscape of Stem Cell Therapies for Stroke Rehabilitation

Stem Cells International, Volume 2025, Issue 1, 2025.
Globally, stroke stands as a principal cause of death and disability, presenting formidable challenges in rehabilitation. Conventional therapeutic modalities often fail to restore functional capabilities fully, underscoring the need for innovative treatment strategies.
Daniel Waszczuk, Shrivats Manikandan, Varsha Manikandan, Erian Stone, Shannon Buehre, Steiv Shore, Manikandan Panchatcharam, Sumitra Miriyala, Alain Chapel   +8 more
wiley   +1 more source

Cytotoxic activity of pyrimethanil on human testicular teratocarcinoma NT2/D1 cells

Heliyon
Fungicides are widely used in the agricultural sector to ensure a safer and larger crop yields. Nevertheless, they represent potentially harmful agents for the environment and living organisms.
Danijela Stanisavljević Ninković, Andrijana Lazić, Milena Aleksić Lilić, Marija Schwirtlich, Perica Vasiljević, Isidora Petrović, Milena Stevanović, Dejan Stojković   +7 more
doaj   +1 more source