Ethanol itself is a holoprosencephaly-inducing teratogen [PDF]
PLoS ONE, 2017 Ethanol is a teratogen, inducing a variety of structural defects in developing humans and animals that are exposed in utero. Mechanisms of ethanol teratogenicity in specific defects are not well understood.
Mingi Hong, R. S. Krauss
semanticscholar +2 more sources
TERATOGEN SEBAGAI FAKTOR RISIKO PADA HIDROSEFALUS: SEBUAH TINJAUAN LITERATUR
PsikoislamediaPenelitian ini bertujuan untuk meninjau pengaruh teratogen terhadap hidrosefalus melalui studi literatur. Hidrosefalus merupakan kondisi neurologis serius yang disebabkan oleh akumulasi cairan serebrospinal di otak. Salah satu faktor risiko utama adalah
I Kadek Okta Dharmadhyaksa +5 more
doaj +2 more sources
Calls to a teratogen information service regarding potential exposures in pregnancy and breastfeeding [PDF]
BMC Pharmacology and Toxicology, 2016 MotherToBaby Utah is a teratogen information service that provides support for pregnant and breastfeeding women and healthcare providers regarding risks of exposures to medications, infections, herbals, homeopathic and dietary medications, chemicals and ...
Sarah C. Campbell +4 more
semanticscholar +2 more sources
CD24 Expression Identifies Teratogen-Sensitive Fetal Neural Stem Cell Subpopulations: Evidence from Developmental Ethanol Exposure and Orthotopic Cell Transfer Models [PDF]
PLoS ONE, 2013 Background Ethanol is a potent teratogen. Its adverse neural effects are partly mediated by disrupting fetal neurogenesis. The teratogenic process is poorly understood, and vulnerable neurogenic stages have not been identified.
J. Tingling +7 more
semanticscholar +2 more sources
Journal of Biological Chemistry, 2001 Valproic acid is widely used to treat epilepsy and bipolar disorder and is also a potent teratogen, but its mechanisms of action in any of these settings are unknown. We report that valproic acid activates Wntdependent gene expression, similar to lithium,
C. Phiel +5 more
semanticscholar +1 more source
EFEK TERATOGEN PEMBERIAN DIETILEN GLIKOL (DEG) PADA MORFOLOGI FETUS MENCIT PUTIH (Mus musculus L.) [PDF]
, 2023 Dietilen glikol (DEG) merupakan bahan kimia industri cair yang berbahaya untuk dikonsumsi karena kurangnya data ilmiah keamanan dan tingginya kasus keracunan yang terjadi.
Siregar, Joyce Artha Roslina
core +1 more source
Pharmacological Safety in Pregnancy: A Systematic Review On the Use of Potentially Teratogenic Drugs
Педиатрическая фармакология, 2017 Objective: To assess the prevalence of potentially teratogenic drug utilization by pregnant women: overall and in the periconceptional period. Methods: The electronic database PubMed/Medline was searched for the following keywords: «pharmacoepidemiology»,
Olga V. Reshetko +2 more
doaj +1 more source
Teratogenicity with Olanzapine
Indian Journal of Psychological Medicine, 2014 Olanzapine, a 2(nd) generation antipsychotic, is in use in the clinical practice for nearly a decade and a half now. It is classified as a category C drug with very few reports of its toxic effects on the fetus. In general, the risk benefit analysis warrants its use in pregnancy.
Sathya Prakash, Rakesh Kumar Chadda
openaire +4 more sources
Role of microRNAs in Alcohol-Induced Multi-Organ Injury
Biomolecules, 2015 Alcohol consumption and its abuse is a major health problem resulting in significant healthcare cost in the United States. Chronic alcoholism results in damage to most of the vital organs in the human body.
Sathish Kumar Natarajan +2 more
doaj +1 more source
Pregnancy outcomes after inadvertent exposure of anti-obesity drugs during pregnancy
Clinical and Experimental Obstetrics & Gynecology, 2021 Backgrounds: To improve health, an increasing number of adults are attempting to lose weight. Moreover, the number of childbearing women targeting weight loss has increased, with a surge in pregnant women exposed to anti-obesity drugs.
Eun Jeong Choi, Jung Yeol Han
doaj +1 more source