Results 41 to 50 of about 13,919 (330)
F1000Research, 2016 Background: Acute high dose exposure to teratogenic chemicals alters the proper development of an embryo leading to infertility, impaired fecundity, and few viable offspring.
A. Killeen, C. Marín de Evsikova
semanticscholar +1 more source
Teratogenicity and Teratogenic Factors
MOJ Anatomy & Physiology, 2017 Teratology is the science that investigates the congenital malformations and their causes Intrauterine exposure to a toxicant particularly in early pregnancy induces embryonic and fetal changes ranging from none up to malformations and stillbirths The teratogenic agents include some viral spirochetal and protozoal infections physical agents as ionizing
openaire +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
A method for human teratogen detection by geometrically confined cell differentiation and migration
Scientific Reports, 2015 Unintended exposure to teratogenic compounds can lead to various birth defects; however current animal-based testing is limited by time, cost and high inter-species variability.
Jiangwa Xing +3 more
semanticscholar +1 more source
Shh signaling in limb bud ectoderm: Potential role in teratogen‐induced postaxial ectrodactyly
, 2005 A variety of teratogens induce the loss of postaxial forelimb structures when administered during mid-gestation to the mouse. Previous studies demonstrated that teratogen exposure is associated with a reduction in zone of polarizing activity (ZPA ...
William J. Scott +9 more
core +1 more source
Anticonvulsants and Chromatin-Genes Expression: A Systems Biology Investigation
Frontiers in Neuroscience, 2020 Embryofetal development is a critical process that needs a strict epigenetic control, however, perturbations in this balance might lead to the occurrence of congenital anomalies.
Thayne Woycinck Kowalski +24 more
doaj +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
International Journal of Environmental Research and Public Health, 2014 This study was undertaken in Gaza, Palestine, in a cohort of babies born in 2011. Hair samples of newborns were analyzed for metal load by DRC-ICP-MS.
P. Manduca, A. Naim, Simona Signoriello
semanticscholar +1 more source
How physicians perceive and utilize information from a teratogen information service: The Motherisk Program [PDF]
, 2004 Background Teratogen information services have been developed around the world to disseminate information regarding the safety of maternal exposures during pregnancy. The Motherisk Program in Toronto, Canada, fields thousands of these inquiries per year.
Park Andrew +8 more
core +2 more sources
Arthritis Care &Research, EarlyView.Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source