Results 61 to 70 of about 13,919 (330)

Teratogen screening using transcriptome profiling of differentiating human embryonic stem cells

Journal of Cellular and Molecular Medicine, 2010
Teratogens are substances that may cause defects in normal embryonic development while not necessarily being toxic in adults. Identification of possible teratogenic compounds has been historically beset by the species‐specific nature of the teratogen ...
Yoav Mayshar, Ofra Yanuka, N. Benvenisty
semanticscholar   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

PREEXISTING MATERNAL DISORDERS – RISK FACTORS FOR NEWBORN CONGENITAL ANOMALIES [PDF]

Romanian Journal of Pediatrics, 2016
Congenital anomalies may be determined by genetic or environmental factors or a combination of the two factors. Maternal disease can affect fetal development through specific effects of metabolic products or maternal antibody transfer.
Elena Braha, Alina Costina Luca
doaj   +1 more source

Queries on medication use during pregnancy: characterisation of the Swiss Teratogen Information Service database. [PDF]

, 2022
AIMS OF THE STUDY Limited information on medication safety may result in concerns on how to treat pregnant and breast-feeding patients. The Swiss Teratogen Information Service (STIS) provides information to healthcare professionals about medications ...
Alice Panchaud, Baumgartner, R., Baumgartner, Rahel, Panchaud, Alice, Simões-Wüst, Ana Paula, Ursula Winterfeld, Rahel Baumgartner, Winterfeld, Ursula, Panchaud, A., Simões-Wüst, A.P., Ana Paula Simões-Wüst, Winterfeld, U.   +11 more
core   +2 more sources

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Effect of retinoic acid on neural tube development in chick embryo [PDF]

Journal of Kerman University of Medical Sciences, 1996
retinoic acid is one of the derivatives of vitamin A.it is used for treatment of dermatitis,but it has different teratogenic effects on developing organs depending on the different stages of embryonic life.neural  tube is made of two different parts ...
M Shariati, M Reza zadeh, M Khaksari, M.R Jafari naveh   +3 more
doaj  

PENGARUH PEMBERIAN FITAMIN E TERHADAP EFEK TERATOGEN DARI EKSTRAK AIR TEMBAKAU ROKOK KRETEK PADA MENCIT PUTIH. [PDF]

, 2008
Telah dilakukan uji pengaruh vitamin E terhadap efek teratogen dari ekstrak air tembakau rokok kretek pada mencit putih. Vitamin E diberikan dengan dosis 130 UI pada hari ke 0 sampai 14 kehamilan, sedangkan ekstrak air tembakau dengan dosis 2 mg/kg BB ...
RAHMADINA, RAHMADINA
core  

When meta‐analyses mislead: Promises and pitfalls in teratology counselling

British Journal of Clinical Pharmacology, EarlyView.
Meta‐analysis has become a central tool for evidence synthesis in clinical teratology, offering the promise of increased statistical power, earlier signal detection and consolidated guidance for teratology counselling. When conducted rigorously and interpreted carefully, pooled analyses can provide clinicians with a structured basis for risk ...
Yusuf Cem Kaplan, Nusret Uysal
wiley   +1 more source

Prevalence of pregnancy and birth outcomes following biologic exposure in immune‐mediated inflammatory diseases: A population‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims Almost 5% of pregnancies are affected by immune‐mediated inflammatory diseases (IMIDs). As treatments become available, understanding their use during pregnancy is important. We aimed to describe maternal, pregnancy and infant outcomes among IMID pregnancies exposed to biologic therapies. Methods Using the Merative™ MarketScan® Commercial Database,
Leah K. Flatman, Lisiane F. Leal, Gabra Nohmie, Anick Bérard   +3 more
wiley   +1 more source

UJI EFEK TERATOGEN KAKAO BUBUK PADA FETUS MENCIT PUTIH

, 2016
Uji efek teratogen kakao bubuk telah dilakukan pada mencit putih. Kakao bubuk diberikan secara per oral dalam bentuk larutan dengan variasi dosis 5.5, 7 dan 8.5 g/kg BB pada hari ke-6 sampai hari ke-15 kehamilan.
NURUL, AFIFAH A
core   +1 more source