Results 21 to 30 of about 13,919 (330)

Current considerations on the teratogens and their effects during pregnancy

open access: yesMedisan, 2022
Introduction: The development reached by teratology as science and the clinical observations made by the scientists,  allowed to establish their principles, represented by a series of factors that determine the capacity of an agent to cause congenital ...
Sandra Yiset Calzadilla Lara   +3 more
doaj  

Concepts in Multifactorial Etiology of Developmental Disorders: Gene-Gene and Gene-Environment Interactions in Holoprosencephaly

open access: yesFrontiers in Cell and Developmental Biology, 2021
Many common developmental disorders are thought to arise from a complex set of genetic and environmental risk factors. These factors interact with each other to affect the strength and duration of key developmental signaling pathways, thereby increasing ...
Hsiao-Fan Lo   +2 more
doaj   +1 more source

Lithium in Pregnancy

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
This article reviews the information available concerning the teratogenic effects o f lithium. Its teratogenicity affects particularly the cardiovascular system, the Ebstein’s anomaly being the most frequent and typical malformation.
Eralp BELLİBAŞ, Işık TUĞLULAR
doaj  

DMSO Concentrations up to 1% are Safe to be Used in the Zebrafish Embryo Developmental Toxicity Assay

open access: yesFrontiers in Toxicology, 2021
Dimethyl sulfoxide (DMSO) is a popular solvent for developmental toxicity testing of chemicals and pharmaceuticals in zebrafish embryos. In general, it is recommended to keep the final DMSO concentration as low as possible for zebrafish embryos ...
Jente Hoyberghs   +5 more
doaj   +1 more source

Pengaruh Teratogen AlCl3 (Aluminium chloride) terhadap Perkembangan Embrio Ayam (Gallus gallus domesticus)

open access: yes, 2023
Teratogen berefek membahayakan terhadap perkembangan embrio. Tujuan penelitian ini untuk mengetahui pengaruh teratogen AlCl3 terhadap perkembangan embrio ayam (Gallus gallus domesticus).
Atifah, Yusni   +4 more
core   +1 more source

Embryonic ethanol exposure disrupts craniofacial neuromuscular integration in zebrafish larvae

open access: yesFrontiers in Physiology, 2023
Forming a vertebrate head involves the meticulous integration of multiple tissue types during development. Prenatal alcohol exposure is known to cause a variety of birth defects, especially to tissues in the vertebrate head.
Ritika Ghosal   +2 more
doaj   +1 more source

In Vitro Micropatterned Human Pluripotent Stem Cell Test (µP-hPST) for Morphometric-Based Teratogen Screening

open access: yesScientific Reports, 2017
Exposure to teratogenic chemicals during pregnancy may cause severe birth defects. Due to high inter-species variation of drug responses as well as financial and ethical burdens, despite the widely use of in vivo animal tests, it’s crucial to develop ...
Jiangwa Xing   +5 more
semanticscholar   +1 more source

Using the electronic medical record to refer women taking category D or X medications for teratogen and contraceptive counseling [PDF]

open access: yes, 2015
BackgroundWomen taking teratogens may not receive teratogen and contraceptive counseling. The objective of this study is to explore the feasibility of an electronic medical record (EMR) alert and referral system to improve teratogen and contraceptive ...
Kao, Kelly   +7 more
core   +1 more source

The Dihydroxy Metabolite of the Teratogen Thalidomide Causes Oxidative DNA Damage

open access: yesChemical Research in Toxicology, 2017
Thalidomide [α-(N-phthalimido)glutarimide] (1) is a sedative and antiemetic drug originally introduced into the clinic in the 1950s for the treatment of morning sickness.
Tasaduq Hussain Wani   +5 more
semanticscholar   +1 more source

Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies

open access: yesFrontiers in Physiology, 2019
Congenital heart disease (CHD) is a significant cause of mortality in infants and adults. Currently human genomic analysis has identified a number of candidate genes in these patients.
Engin Deniz   +7 more
doaj   +1 more source

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