Results 201 to 210 of about 26,590 (258)

Teratogenic effects of serotonin

The Journal of Pediatrics, 1963
Serotonin given subcutaneously twice daily during pregnancy to rats produced congenital malformations, macerations, and resorptions of the offspring in a high percentage when given in the proper dose. Two cases of carcinoid in human beings are described briefly. In one the patient probably had carcinoid during all 4 pregnancies, 3 of which resulted in
D V, REDDY, F H, ADAMS, C, BAIRD
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Teratogenic Effects of Anticonvulsants

Archives of Neurology, 1981
The incidence of malformations in fetal mice exposed to phenytoin depends on drug dosage and the strain of mice. Animal research also suggests that most anticonvulsants are teratogenic in experimental animals when large doses are used, but the effect of valproate sodium on the fetus is poorly known.
G W, Paulson, R B, Paulson
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TERATOGENIC EFFECT OF ANTICONVULSANT DRUGS

Obstetrical & Gynecological Survey, 1976
Multiple malformations in all four children of a mother taking anticonvulsant drugs are reported, along with the extended family pedigree.
M, Waziri, V, Ionasescu, H, Zellweger
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Teratogenic Effects of Antiepileptic Medications

Neurologic Clinics, 2009
Data on clinical teratogenicity are at best derived from carefully conducted observational studies, whereas randomized, controlled trials have no place in this research area. We can only expect level B recommendations and lower. New relevant information has become available during the last 5 years on pregnancy outcomes with 3 of the most frequently ...
Torbjörn, Tomson, Dina, Battino
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TERATOGENIC EFFECTS OF ASIAN INFLUENZA

Journal of the American Medical Association, 1959
That a cause and effect relationship exists between a maternal viral infection during the first trimester of pregnancy and congenital defects in the child remains inconclusive, except in rubella, since most of the studies are of a retrospective type.
M G, WILSON, H L, HEINS, D T, IMAGAWA, J M, ADAMS   +3 more
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Teratogenic effects of aliphatic nitriles

Teratology, 1981
AbstractIntraperitoneal injection of acrylonitrile at 1.51–2.26 mmole/kg (80–120 mg/kg) or propionitrile at 0.54–1.51 mmole/kg (30–83 mg/kg) on the morning of Day 8 of gestation in the hamster induced exencephaly, encephalocoeles, and rib fusions and bifurcations in the offspring.
C C, Willhite, V H, Ferm, R P, Smith
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Possible teratogenic effects of gold

Journal of Paediatrics and Child Health, 1980
There are few reports of the outcome of pregnancies exposed to gold in utero. We report an abnormal babe resulting from a pregnancy inadvertently exposed to gold. The cleft lip and palate and brain abnormalities are similar in type to those seen in rats and rabbits exposed to gold in utero.
J G, Rogers, R M, Anderson, C W, Chow, G L, Gillam, L, Markman   +4 more
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Teratogenic effects of gravitational changes

Advances in Space Research, 1994
In investigating the effect of gravitational changes on development, it is instructive to think of altered gravity (delta g) as a teratogen--that is, an environmental factor influencing development. Observed effects on skeletal development include: suppression of morphogenesis in centrifuged mouse limb buds; advanced fusion stages in centrifuged ...
P J, Duke, D, Montufar-Solis, E, Daane
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Do Anticonvulsants Have a Teratogenic Effect?

Archives of Neurology, 1974
Study of 284 births in Rochester, Minn, to 138 women who had epilepsy suggests (as have other studies) that there is an increased incidence of malformations among the offspring of women taking anticonvulsants. Among the 141 children born to mothers taking one or more of the anticonvulsants, ten had serious malformations, including five with congenital ...
J F, Annegers, L R, Elveback, W A, Hauser, L T, Kurland   +3 more
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Teratogenic effect of maternal zinc deficiency and its co‐teratogenic effect with cadmium

Teratology, 1985
AbstractThe teratogenic effects of feeding pregnant mice with the levels of zinc that were severely deficient (0.5 ppm), marginally deficient (10 ppm), or zinc replete (50 ppm) were studied. All groups of animals were fed the experimental diet from 1–18 days of gestation (dg) except for one additional group which received 0.5 ppm Zn diet from 5–14 dg ...
F, Sato, T, Watanabe, E, Hoshi, A, Endo
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