Results 51 to 60 of about 26,590 (258)
TERATOGENIC PROPERTIES OF DRUGS. BACKGROUND INFORMATION
Педиатрическая фармакология, 2013 The article presents the most significant steps in the development of ideas about drugs’ effects on fetus. It features the thalidomide tragedy and features of thalidomide teratogenic properties, as well as data on thalidomide syndrome prevention ...
A. A. Ivanova +2 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott +7 more
wiley +1 more source
TERATOGENIC EFFECTS OF DRUGS ON THE ORGANISM OF A FUTURE CHILD DURING FETAL STAGE OF DEVELOPMENT
Педиатрическая фармакология, 2011 Article assesses the impact of adverse factors on intrauterine development of the child, first of all, drugs. The author stresses that the importance of drug safety (D) is due to the large number of unintended pregnancies worldwide.
S.A. Sher
doaj +2 more sources
Teratogenic effects of Metoprolol in the chick embryos
The Iraqi Journal of Veterinary Medicine, 2015 This study was conducted to demonstrate the effect of Metoprolol on chicken embryos during the period of cuddling automated .This study was completed in Babylon hatchery dedicated to the production of chick chickens, which is located in the province of ...
Abbas Razzaq Abed
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh +4 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland +48 more
wiley +1 more source
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Teratogenicity of Anticonvulsants (AEDs)
Pediatric Neurology Briefs, 1992 The risks of teratogenic effects of AEDs are reported from Erasmus University, Rotterdam, The Netherlands.
J Gordon Millichap
doaj +1 more source
Teratogenic Effects of Hyperbaric Oxygen.
Experimental Biology and Medicine, 1964 SummaryPregnant golden hamsters in early stages of gestation were exposed to hyperbaric oxygen at 3.0, 3.6, and 4.0 atmospheres for periods of 3 and 2 hours. One-fourth of the mothers developed central nervous system signs during treatment and were sacrificed.
openaire +2 more sources
Epilepsia, EarlyView.Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei +10 more
wiley +1 more source