Results 111 to 120 of about 21,579 (291)
Environmental Toxicology, EarlyView.ABSTRACT Anthropogenic activities and the large volume of compounds released into the environment are sources of contamination for plants, animals, and humans. The herbicide monosodium methyl arsenate (MSMA) ranks among the best‐selling agricultural pesticides in Brazil.
Daniel Moreira Melo +3 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.
Pedro Junqueira Fleury Silva +12 more
wiley +1 more source
Pesticides and Hypospadias in Southern Brazil: An Ecological Study
Environmental Toxicology, EarlyView.ABSTRACT Rio Grande do Sul ranks among the Brazilian states with the highest pesticide consumption and one of the highest prevalences of hypospadias, a congenital anomaly often associated with prenatal exposure to endocrine‐disrupting chemicals. We assessed the relationship between prenatal pesticide exposure and hypospadias risk through an ecological ...
Ricardo Rohweder +4 more
wiley +1 more source
Structural themes of cereblon‐recruiting degraders: selected recent examples
Acta Crystallographica Section F, EarlyView.Structural studies of cereblon‐recruiting degrader complexes have transformed our understanding of targeted protein degradation. This review discusses selected examples of how X‐ray crystallography and cryogenic‐electron microscopy have enabled the structure‐guided optimization of heterobifunctional degraders and molecular‐glue degraders.
Sana Ahmed, Michael Rowley
wiley +1 more source
EVALUATION OF TERATOGENICITY EFFECTS OF ETHANOLIC EXTRACTS OF BINAHONG LEAVES (ANREDERA CORDIFOLIA (TEN) STEENIS) IN WISTAR RAT [PDF]
, 2014 Objective: The aim of this study was to evaluate teratogenicity effect of ethanolic extract of binahong (Anredera cordifolia (Ten.) Steenis) leaves in Wistar rats. Methods: The teratogenicity test were done in 5 groups of rat i. e.
Fitria, Via +2 more
core +1 more source
Pharmacokinetics and metabolism of valproate : In relation to prevention of valproate teratogenicity [PDF]
Pharmacokinetics and metabolism of valproate (VPA) has been discussed in relation to the risk and prevention of VPA teratogenicity. Prospective epidemiological studies have shown that high VPA dosages (≧1000 mg/day) and high VPA concentrations (≧ 70$ \mu
近藤, 毅, Kondo, Tsuyoshi
core
Systemic Treatment of Psoriasis: Current Evidence on Efficacy and Safety
The Journal of Dermatology, EarlyView.ABSTRACT Systemic treatments for moderate‐to‐severe plaque psoriasis have been advanced from broad immunosuppressants up to agents more selectively targeting cytokines, cytokine receptors, or intracellular signaling. The current systemic treatments mainly consist of conventional systemic agents, biologics targeting tumor necrosis factor (TNF)‐α ...
Teppei Hagino, Naoko Kanda
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective An increasing number of women of childbearing age worldwide are using glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and are advised to use effective contraception during treatment. Nevertheless, maternity services are encountering increasing numbers of women exposed to GLP‐1 RAs shortly before conception or during pregnancy ...
Katherine G. Y. Lau +6 more
wiley +1 more source
Integrative Zoology, EarlyView.This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu +5 more
wiley +1 more source