Results 91 to 100 of about 21,579 (291)

Ethanol teratogenicity : the aetiological importance of zinc and metallothionein / by Luke Charles Carey.

open access: yes, 2002
"August 2002"Bibliography: leaves 141-176.ix, 179 leaves : ill. (some col.) ; 30 cmChanges in maternal-foetal zinc homeostasis resulting in a foetal deficiency may be an important contributing factor in ethanol-realted teratogenicity.
Carey, Luke Charles
core  

Diffusion MRI‐Based Fetal Thermometry Using Cerebrospinal Fluid: A Translational Feasibility Study

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Noninvasive fetal temperature assessment could improve MRI safety monitoring and provide insight into fetal physiology. Diffusion MRI is a potential approach because water diffusivity in free fluids is temperature dependent. However, the applicability of adult‐derived diffusivity–temperature calibration to neonatal and fetal CSF ...
Nahla M. H. Elsaid   +5 more
wiley   +1 more source

Assessment of fetal risk associated with exposure to cancer chemotherapy during pregnancy: a multicenter study

open access: yesBrazilian Journal of Medical and Biological Research, 2001
The objective of the present study was to evaluate and quantify fetal risks involved in the administration of cancer chemotherapy during gestation, as well as to assess the long-term effects on the exposed children.
R.M. Peres   +7 more
doaj   +1 more source

Nonclinical teratogenicity safety assessment of CRBN-engaging targeted protein degraders: Points to consider.

open access: yes
Targeted protein degraders (or degraders) are an emerging small molecule drug modality with transformative therapeutic potential. Currently, most degraders are developed for severe life-threatening disorders and engage the E3 ligase cereblon. One barrier
Hemkens, Michelle   +11 more
core   +1 more source

A chick model for the mechanisms of mustard gas neurobehavioral teratogenicity [PDF]

open access: yes, 2005
The chemical warfare blistering agent, sulfur mustard (SM), is a powerful mutagen and carcinogen. Due to its similarity to the related chemotherapy agents nitrogen mustard (mechlorethamine), it is expected to act as a developmental neurotoxicant.
Brodsky, B   +5 more
core   +1 more source

Exploring women's experiences and perceptions regarding the pharmacological management of hyperemesis gravidarum: a qualitative study

open access: yesJournal of Pharmacy Practice and Research, EarlyView.
Abstract Background Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy with potential sequelae including hypovolaemia, electrolyte imbalance, and malnutrition, which can result in adverse maternal–foetal outcomes. Aim To explore Australian women's experiences and perceptions regarding the pharmacological management of HG ...
Timothy R. McNamara   +5 more
wiley   +1 more source

Neurosurgery and pregnancy

open access: yesJournal of Neuroanaesthesiology and Critical Care, 2014
Pregnant patients rarely present with neurosurgical emergencies, but can cause significant morbidity and mortality to the mother and the foetus. Physiological changes of pregnancy in relevance to neurosurgery, effects of anaesthetic agents on the foetus,
Rajkumar Subramanian   +4 more
doaj   +1 more source

Anatomical, behavioral, and cognitive teratogenicity associated with valproic acid: a systematic review

open access: yes
Background. Recent guidance from UK health authorities strongly cautions against the use of valproic acid (VPA) in persons under 55 because of reevaluated risk of teratogenicity. Objective.
Lo, HKY   +8 more
core   +1 more source

Epilepsy surgery through a reproductive lifespan lens

open access: yes
Epilepsia, EarlyView.
Aisha A. Abdulrazaq   +2 more
wiley   +1 more source

Molecular Glue Degraders in Early Development for Cancer Therapy

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Molecular glue degraders are an emerging class of small molecule allosteric modulators that induce or stabilize protein‐protein interactions, enabling targeted degradation of previously intractable proteins. By redirecting E3 ligases to recognize neosubstrates, proteins that are not typically recognized by a specific E3 ubiquitin ligase, they ...
E. Sila Ozdemir   +4 more
wiley   +1 more source

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